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Building an Evidence Base for Weight Loss Strategies among those with Chronic SCI

Award Number: 90IFRE0022
ORGANIZATION: NATIONAL INSTITUTE ON DISABILITY, INDEPENDENT LIVING, AND REHABILITATION RESEARCH
OPDIV: ACL
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: OTHER
PERIOD OF PERFORMANCE START DATE: 09/30/2018
PERIOD OF PERFORMANCE END DATE: 09/29/2022

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Building an Evidence Base for Weight Loss Strategies among those with Chronic SCI - The obesity epidemic that has swept across our nation affects significantly more Americans living with spinal cord injury (SCI) than Americans generally, putting them at increased risk for chronic conditions such as diabetes, hypertension, high cholesterol, and cardiovascular disease. Excess weight may also impact their function and result in further limitations. Although weight loss research has proliferated, less research has addressed weight loss strategies for those with SCI. Fundamental components of weight loss include eating a balanced diet and increasing physical activity, yet these behaviors may be more challenging for people with SCI to adopt than for those in the general population. This study proposes to advance the evidence base by systematically testing evidence-based weight loss strategies that are adapted using a community-based participatory research approach to meet the needs of those with SCI. The overarching aim of this proposal is to develop an effective evidence-based multicomponent weight loss intervention for people with SCI with the intent to improve their health and function. The study proposes to conduct a series of studies to systematically gather evidence on their effectiveness and usability that can be shared with a SCI Consumer Group to help guide the development of an effective multicomponent intervention that addresses the unique issues facing people with SCI in adopting lifestyle changes that promote weight loss. Primary Aim 1: Use community-based participatory research (CBPR) to systematically develop a multicomponent weight loss intervention for people with chronic SCI. CBPR will (a) guide further adaptations of the GLB AIM to address unique issues facing those with chronic SCI and (b) inform use of specific weight loss strategies within the new GLB SCI intervention. Primary Aim 2: Evaluate the effectiveness and usability of using prepackaged/portion controlled meals in achieving weight loss over 13 weeks. Hypothesis 2.1: Use of prepackaged/portion controlled meals will yield significant weight loss over 13 weeks, averaging at least 5% of participants’ starting weight. Hypothesis 2.2: Participants given prepackaged/portion controlled meals for 13 weeks will positively rate the strategy, defined as an average score of 3.5 or higher on a 1 – 5 scale. Primary Aim 3: Evaluate the effectiveness and usability of using enhanced self-monitoring in achieving weight loss over 13 weeks. Hypothesis 3.1: Use of enhanced self-monitoring will yield significant weight loss over 13 weeks, averaging at least 5% of participants’ starting weight. Hypothesis 3.2: Participants provided enhanced self-monitoring for 13 weeks will positively rate the strategy, defined as an average score of 3.5 or higher on a 1 – 5 scale. Primary Aim 4: Evaluate the effectiveness and usability of using the adapted GLB SCI in achieving weight loss over 13 weeks. Hypothesis 4.1: Use of the adapted GLB SCI will yield significant weight loss over 13 weeks, averaging at least 5% of participants’ starting weight. Hypothesis 4.2: Participants provided the adapted GLB SCI for 13 weeks will positively rate the strategy, defined as an average score of 3.5 or higher on a 1 – 5 scale. Primary Aim 5: Obtain preliminary evidence on effectiveness and usability data of the combined GLB SCI+ multicomponent intervention for achieving weight loss over 13 weeks. Hypothesis 5.1: Use of the combined GLB SCI+ will yield significant weight loss over 13 weeks, averaging at least 5% of participants’ starting weight. Hypothesis 5.2: Participants provided combined GLB SCI+ for 13 weeks will positively rate the strategy, defined as an average score of 3.5 or higher on a 1 – 5 scale.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2025 ( Subtotal = $0 )
2025	2020	BAYLOR RESEARCH INSTITUTE	3434 LIVE OAK ST	DALLAS	TX	75204	DALLAS	USA	ACL National Institute on Disability, Independent Living, and Rehabilitation Research	04	3	10/28/2024	ADMINISTRATIVE SUPPLEMENT ( + OR - ) (DISCRETIONARY OR BLOCK AWARDS)	$0
														Subtotal = $0

Issue Date FY: 2022 ( Subtotal = $0 )
2022	2018	Baylor Research Institute	2001 Bryan St Ste 2200	Dallas	TX	75201	DALLAS	USA	ACL National Institute on Disability, Independent Living, and Rehabilitation Research	03	3	6/22/2022	ADMINISTRATIVE SUPPLEMENT ( + OR - ) (DISCRETIONARY OR BLOCK AWARDS)	$0
2022	2018	Baylor Research Institute	2001 Bryan St Ste 2200	Dallas	TX	75201	DALLAS	USA	ACL National Institute on Disability, Independent Living, and Rehabilitation Research	04	3	6/29/2022	ADMINISTRATIVE SUPPLEMENT ( + OR - ) (DISCRETIONARY OR BLOCK AWARDS)	$0
														Subtotal = $0

Issue Date FY: 2021 ( Subtotal = $0 )
2021	2020	Baylor Research Institute	2001 BRYAN ST STE 2200	DALLAS	TX	75201	DALLAS	USA	ACL National Institute on Disability, Independent Living, and Rehabilitation Research	01	3	4/30/2021	OTHER REVISION	$0
2021	2020	Baylor Research Institute	2001 BRYAN ST STE 2200	DALLAS	TX	75201	DALLAS	USA	ACL National Institute on Disability, Independent Living, and Rehabilitation Research	02	3	9/17/2021	EXTENSION WITH OR WITHOUT FUNDS	$0
2021	2019	Baylor Research Institute	2001 BRYAN ST STE 2200	DALLAS	TX	75201	DALLAS	USA	ACL National Institute on Disability, Independent Living, and Rehabilitation Research	02	3	9/17/2021	EXTENSION WITH OR WITHOUT FUNDS	$0
2021	2019	Baylor Research Institute	2001 BRYAN ST STE 2200	DALLAS	TX	75201	DALLAS	USA	ACL National Institute on Disability, Independent Living, and Rehabilitation Research	01	3	4/30/2021	OTHER REVISION	$0
														Subtotal = $0

Issue Date FY: 2020 ( Subtotal = $197,771 )
2020	2020	Baylor Research Institute	2001 Bryan St Ste 2200	Dallas	TX	75201	DALLAS	USA	ACL National Institute on Disability, Independent Living, and Rehabilitation Research	00	3	7/1/2020	NON-COMPETING CONTINUATION	$197,771
2020	2018	Baylor Research Institute	2001 Bryan St Ste 2200	Dallas	TX	75201	DALLAS	USA	ACL National Institute on Disability, Independent Living, and Rehabilitation Research	01	2	6/25/2020	OTHER REVISION	$0
														Subtotal = $197,771

Issue Date FY: 2019 ( Subtotal = $198,288 )
2019	2019	Baylor Research Institute	2001 Bryan St Ste 2200	Dallas	TX	75201	DALLAS	USA	ACL National Institute on Disability, Independent Living, and Rehabilitation Research	00	2	8/13/2019	NON-COMPETING CONTINUATION	$198,288
														Subtotal = $198,288

Issue Date FY: 2018 ( Subtotal = $199,999 )
2018	2018	BAYLOR RESEARCH INSTITUTE, THE	3310 LIVE OAK STE 501	DALLAS	TX	75204	DALLAS	USA	ACL National Institute on Disability, Independent Living, and Rehabilitation Research	00	1	9/13/2018	NEW	$199,999
														Subtotal = $199,999

Grand Total All Awards = $596,058

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Building an Evidence Base for Weight Loss Strategies among those with Chronic SCI

Award Number: 90IFRE0022

ORGANIZATION: NATIONAL INSTITUTE ON DISABILITY, INDEPENDENT LIVING, AND REHABILITATION RESEARCH

OPDIV: ACL

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: OTHER

PERIOD OF PERFORMANCE START DATE: 09/30/2018

PERIOD OF PERFORMANCE END DATE: 09/29/2022

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