Intensive attention training to treat brain fog in individuals with Long-Covid - According to recent estimates, one in seven American adults who have had Covid-19 is currently experiencing Long-Covid symptoms. Deficits in attention, executive functions and memory are common in people with Long-Covid, and are often referred to as “brain fog”. The functional impact of brain fog can be profound, affecting individuals’ abilities to perform daily activities and maintain social relationships. While the phenomenon of brain fog is widely documented, very little is known about potential treatments. However, useful insight can be drawn from research on people with mild traumatic brain injuries, who often experience similar cognitive deficits, and are known to benefit from Attention Processing Training.
In this project, a team of scientists and clinicians will work with stakeholders to develop an intervention protocol for people with Long-Covid brain fog. The objectives are 1) to assess the feasibility and acceptability of intensive Attention Processing Training in a sample of people with Long-Covid; 2) to identify attention-related outcome measures that would be appropriate to use in a future clinical trial of the intervention, and 3) to provide a preliminary evaluation of the efficacy of the intervention compared to waitlist control.
Anticipated outcomes are a treatment protocol targeting cognitive deficits in individuals with Long-Covid, and the data necessary for the design of a future clinical trial that will investigate the effectiveness of the proposed intervention. The expected products will be peer-reviewed publications and research presentations, an intervention manual, and a database that could be used to assess intervention effectiveness in a future clinical trial.