Rusk Rehabilitation serves New York City and the tri-state area (New York, New Jersey, and Connecticut) and is ranked #8 in the United States by U.S. News and World Report which provides an excellent environment for generating new knowledge and scientific evidence to improve outcomes for all persons with TBI. The RRTBIMS is a collaborative endeavor involving Rusk Rehabilitation, NYU Langone Hospital (NYULH), Bellevue Hospital Center (Bellevue), and NYU Langone Brooklyn. To accomplish our goals, the RRTBIMS will enroll 35 individuals with TBI/year into the TBIMS National Database. The site-specific project will investigate the effectiveness of a remotely delivered, patient-centered wellness program, “Mindfulness, Exercise, Nutrition to Optimize Recovery (MENTOR)”, that focuses on mindfulness, exercise, nutrition, and wellness concepts, as well as peer/social support components to improve health-related quality of life. The module project will define, characterize and explore the relationships between individuals with TBI and their support system over time as the family unit navigates the management of chronic TBI. These studies will add to the evidence-base to improve services and supports that extend the continuum of care for individuals with TBI and maximize quality of life and community participation. Finally, our plan of Dissemination and Knowledge Translation builds upon our extensive past experience with the TBIMS program. Drs. Bushnik, Im and Flanagan are well-recognized past participants of the TBIMS program and the research study staff have been with the RRTBIMS for at least 5 years. With this wealth of experience, the RRTBIMS will continue to be a valued contributor to the 2022-2027 TBIMS grant cycle.