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| Issue Date FY: 2024 ( Subtotal = $66,729,772 ) (Continued on the next page) |
| 2024 | 2024 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-1712 | CUYAHOGA | USA | R01AI172944 | Development and evaluation of a second-generation fungerp for systemic and cutaneous C. auris infection | 000 | 2 | NIH | 11/1/2023 | $583,710 |
| 2024 | 2024 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-1712 | CUYAHOGA | USA | R01NS128226 | Structural diversity of cervid prions and phenotypic variation of chronic wasting disease | 001 | 2 | NIH | 4/25/2024 | $28,174 |
| 2024 | 2024 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-1712 | CUYAHOGA | USA | R01NS128226 | Structural diversity of cervid prions and phenotypic variation of chronic wasting disease | 000 | 2 | NIH | 3/4/2024 | $362,251 |
| 2024 | 2024 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-1712 | CUYAHOGA | USA | F30HD110088 | Dissecting the role of IER3IP1 in neurogenesis and brain malformation | 000 | 2 | NIH | 3/13/2024 | $52,694 |
| 2024 | 2024 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-1712 | CUYAHOGA | USA | R01HL167159 | 5 D impulse mapping in the embryonic heart | 000 | 2 | NIH | 2/8/2024 | $619,134 |
| 2024 | 2024 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-1712 | CUYAHOGA | USA | R03AG080175 | Bacterial triggers of neural inflammation. | 000 | 2 | NIH | 11/16/2023 | $144,900 |
| 2024 | 2024 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-1712 | CUYAHOGA | USA | R01MH129294 | The role of subcortical inputs to the hippocampal CA3 region in fear memory | 000 | 2 | NIH | 11/1/2023 | $355,606 |
| 2024 | 2024 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-1712 | CUYAHOGA | USA | R01CA269816 | Detection, Radiosensitization and Theranostic Targeting of Metastatic Breast Cancer by PTPmu | 001 | 2 | NIH | 4/16/2024 | $33,408 |
| 2024 | 2024 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-1712 | CUYAHOGA | USA | R01CA269816 | Detection, Radiosensitization and Theranostic Targeting of Metastatic Breast Cancer by PTPmu | 000 | 2 | NIH | 11/2/2023 | $601,330 |
| 2024 | 2024 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-1712 | CUYAHOGA | USA | R01CA269354 | Magnetic Resonance Fingerprinting of Tumor Vascular Perfusion and Acidosis | 001 | 2 | NIH | 4/17/2024 | $33,184 |
| 2024 | 2024 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-1712 | CUYAHOGA | USA | R01CA269354 | Magnetic Resonance Fingerprinting of Tumor Vascular Perfusion and Acidosis | 000 | 2 | NIH | 11/8/2023 | $597,290 |
| 2024 | 2024 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-1712 | CUYAHOGA | USA | R35GM148115 | H3K9me3-based gene silencing and cellular identity | 000 | 2 | NIH | 1/4/2024 | $362,250 |
| 2024 | 2024 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-1712 | CUYAHOGA | USA | R01AI171104 | Selective Inhibitors of T Cell Activation Target Exportin-1 at Cys528 to Suppress Pathological T Cell Activation | 000 | 2 | NIH | 12/14/2023 | $466,445 |
| 2024 | 2024 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-1712 | CUYAHOGA | USA | R01AG080924 | SSH1-Nrf2 nexus in tipping the balance between degeneration and protection in tauopathies. | 000 | 2 | NIH | 11/15/2023 | $460,922 |
| 2024 | 2024 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-1712 | CUYAHOGA | USA | R03AG077132 | Evaluation of genetic and metabolic markers in the development of urinary urgency incontinence | 000 | 2 | NIH | 11/16/2023 | $74,596 |
| 2024 | 2024 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-1712 | CUYAHOGA | USA | K01DK128304 | Using transcriptomics and ex vivo organotypic models to discover mechanisms of APOL1-associated podocytopathies | 000 | 2 | NIH | 11/8/2023 | $130,741 |
| 2024 | 2024 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-1712 | CUYAHOGA | USA | R01CA269604 | MR Fingerprinting based Quantitative Imaging and Analysis Platform (MRF-QIA) for brain tumors. | 001 | 2 | NIH | 4/16/2024 | $27,961 |
| 2024 | 2024 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-1712 | CUYAHOGA | USA | R01CA269604 | MR Fingerprinting based Quantitative Imaging and Analysis Platform (MRF-QIA) for brain tumors. | 000 | 2 | NIH | 1/3/2024 | $503,308 |
| 2024 | 2024 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-1712 | CUYAHOGA | USA | R01GM143256 | "Developing A Comprehensive Toolkit for Chemical Inducible Epigenome Remodeling" | 000 | 3 | NIH | 4/10/2024 | $289,800 |
| 2024 | 2024 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-1712 | CUYAHOGA | USA | R01HL156928 | Altered Circadian Rhythm Regulation in Cystic Fibrosis | 000 | 3 | NIH | 3/21/2024 | $563,589 |
| 2024 | 2024 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-1712 | CUYAHOGA | USA | R01CA266050 | The Microbiome and Mucosal Immunity in Cervical Cancer Disparities | 001 | 3 | NIH | 4/17/2024 | $27,969 |
| 2024 | 2024 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-1712 | CUYAHOGA | USA | R01CA266050 | The Microbiome and Mucosal Immunity in Cervical Cancer Disparities | 000 | 3 | NIH | 3/18/2024 | $503,454 |
| 2024 | 2024 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-1712 | CUYAHOGA | USA | R01HL160857 | Mechanisms of oxygen off-loading from red blood cells in murine models of human disease | 000 | 3 | NIH | 1/17/2024 | $591,248 |
| 2024 | 2024 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-1712 | CUYAHOGA | USA | R21EB032644 | Background Oriented Schlieren (BOS) Visualization for Evaluation of Risk in Aerosol-Generating Procedures | 000 | 3 | NIH | 11/9/2023 | $170,026 |
| 2024 | 2024 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-1712 | CUYAHOGA | USA | R01ES033670 | Targets and targeting of immunometabolism in chronic PM2.5 exposure | 000 | 3 | NIH | 11/17/2023 | $402,500 |
| 2024 | 2024 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-1712 | CUYAHOGA | USA | R61AI169629 | The role of RNA m6A modification in the regulation of HIV latency and reactivation | 000 | 3 | NIH | 3/25/2024 | $715,479 |
| 2024 | 2024 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-1712 | CUYAHOGA | USA | R01HL157405 | Tyrosine Kinases and Thrombosis | 000 | 3 | NIH | 1/19/2024 | $400,304 |
| 2024 | 2024 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-1712 | CUYAHOGA | USA | R01HL156987 | Impact of microfibril turnover on vascular development and disease | 002 | 3 | NIH | 11/14/2023 | $362,250 |
| 2024 | 2024 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-1712 | CUYAHOGA | USA | F30DK128944 | AKR1a1 as a novel therapeutic target for Non-Alcoholic Fatty Liver Disease | 000 | 3 | NIH | 1/12/2024 | $52,694 |
| 2024 | 2024 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-1712 | CUYAHOGA | USA | F31NS122176 | Identifying novel targets and mechanistic role of 8,9 unsaturated sterol accumulation on enhancement of oligodendrocyte formation | 003 | 3 | NIH | 3/22/2024 | $0 |
| 2024 | 2024 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-1712 | CUYAHOGA | USA | F31NS122176 | Identifying novel targets and mechanistic role of 8,9 unsaturated sterol accumulation on enhancement of oligodendrocyte formation | 001 | 3 | NIH | 3/19/2024 | -$19,691 |
| 2024 | 2024 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-1712 | CUYAHOGA | USA | F31NS122176 | Identifying novel targets and mechanistic role of 8,9 unsaturated sterol accumulation on enhancement of oligodendrocyte formation | 000 | 3 | NIH | 11/22/2023 | $32,650 |
| 2024 | 2024 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-1712 | CUYAHOGA | USA | R01AG076051 | Mechanism of white matter pathology in Alzheimer's disease | 000 | 3 | NIH | 11/3/2023 | $546,748 |
| 2024 | 2024 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-1712 | CUYAHOGA | USA | D43TW012260 | Strengthening Research Capacity in Innovative Global Health Technologies for Non-Communicable Diseases in Uganda | 000 | 3 | NIH | 2/9/2024 | $246,449 |
| 2024 | 2024 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-1712 | CUYAHOGA | USA | R01AG085316 | Identifying T cell determinants of heritable Frontotemporal dementia | 000 | 1 | NIH | 3/13/2024 | $604,649 |
| 2024 | 2024 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-1712 | CUYAHOGA | USA | R25NS135590 | Research Immersion in Brain, Spinal cord (RIBS), & Peripheral nerves for URM High School Students | 000 | 1 | NIH | 12/22/2023 | $135,000 |
| 2024 | 2024 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-1712 | CUYAHOGA | USA | R37CA278982 | Role of LRG1 in colorectal cancer tumorigenesis | 000 | 1 | NIH | 2/1/2024 | $368,288 |
| 2024 | 2024 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-1712 | CUYAHOGA | USA | R00GM143550 | Integration of metabolism and chromatin in regulating gene expression in vivo | 001 | 3 | NIH | 4/16/2024 | $183 |
| 2024 | 2024 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-1712 | CUYAHOGA | USA | R00GM143550 | Integration of metabolism and chromatin in regulating gene expression in vivo | 000 | 3 | NIH | 12/26/2023 | $249,000 |
| 2024 | 2024 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-1712 | CUYAHOGA | USA | K08DK135933 | A comprehensive approach to understanding the genetic causes of urinary stone disease: combining monogenic and polygenic analyses | 000 | 1 | NIH | 12/22/2023 | $163,036 |
| 2024 | 2024 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-1712 | CUYAHOGA | USA | R13NS137719 | Cleveland NeuroDesign Entrepreneurs Workshop | 000 | 1 | NIH | 3/27/2024 | $24,724 |
| 2024 | 2024 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-1712 | CUYAHOGA | USA | R21CA288449 | Roles of gut-breast axis in breast pathophysiology | 000 | 1 | NIH | 4/5/2024 | $225,803 |
| 2024 | 2024 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-1712 | CUYAHOGA | USA | R21CA280426 | Development of a novel, CNS-penetrant synthetic triterpenoid for pediatric high-grade glioma. | 000 | 1 | NIH | 11/30/2023 | $225,803 |
| 2024 | 2024 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-1712 | CUYAHOGA | USA | R01CA287672 | Optimizing anti-wild-type IDH1 therapy in pancreatic cancer | 000 | 1 | NIH | 2/16/2024 | $690,929 |
| 2024 | 2024 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-1712 | CUYAHOGA | USA | R01CA275910 | MIZ1 Activation in Triple-negative Breast Cancer Racial Disparities | 000 | 1 | NIH | 1/11/2024 | $617,723 |
| 2024 | 2024 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-1712 | CUYAHOGA | USA | R21CA280151 | Exploring SGLTs as Theranostic Targets for Cancer Metastasis | 000 | 1 | NIH | 11/28/2023 | $236,000 |
| 2024 | 2024 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-1712 | CUYAHOGA | USA | R01MH130476 | The role of heparan sulfate modification on neurexin1 in synapse development | 000 | 1 | NIH | 11/17/2023 | $376,437 |
| 2024 | 2024 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-1712 | CUYAHOGA | USA | R03CA273468 | c-Myc regulation by TGF-beta signaling as a therapeutic target in Osteosarcoma | 000 | 1 | NIH | 11/22/2023 | $80,500 |
| 2024 | 2024 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-1712 | CUYAHOGA | USA | R21ES036031 | Healthy Futures Research Study: Linking somatic mutation rate with baseline exposure in East Palestine | 000 | 1 | NIH | 2/8/2024 | $161,000 |
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