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 | Issue Date FY: 2024 ( Subtotal = $36,353,364 ) (Continued on the next page) |
| | 2024 | 2024 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01AG076448 | TREM2 Genotype-Informed Drug Repurposing and Combination Therapy Design for Alzheimer?s Disease | 000 | 3 | NIH | 4/15/2024 | $809,747 |
| | 2024 | 2024 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | K23MD017284 | Improving Black sarcoidosis patients? care with a collaboratively developed, patient centered program | 000 | 3 | NIH | 3/22/2024 | $143,913 |
| | 2024 | 2024 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01NS124081 | lncRNA regulation of glioblastoma progression and therapeutic resistance | 001 | 3 | NIH | 4/25/2024 | $38,304 |
| | 2024 | 2024 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01NS124081 | lncRNA regulation of glioblastoma progression and therapeutic resistance | 000 | 3 | NIH | 12/4/2023 | $492,501 |
| | 2024 | 2024 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01NS123532 | Understanding role of circadian disruption in pathogenesis of MS | 001 | 3 | NIH | 4/25/2024 | $32,955 |
| | 2024 | 2024 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01NS123532 | Understanding role of circadian disruption in pathogenesis of MS | 000 | 3 | NIH | 2/13/2024 | $423,704 |
| | 2024 | 2024 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01HL160747 | Gut-microbial metabolism of aromatic amino acids and cardiovascular disease | 000 | 3 | NIH | 11/22/2023 | $502,296 |
| | 2024 | 2024 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01EY032459 | Molecular Mechanisms of TULP1-Mediated Photoreceptor Degeneration | 000 | 3 | NIH | 4/19/2024 | $402,500 |
| | 2024 | 2024 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01NS124547 | The mammalian multi-tRNA synthetase complex | 001 | 3 | NIH | 4/25/2024 | $33,731 |
| | 2024 | 2024 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01NS124547 | The mammalian multi-tRNA synthetase complex | 000 | 3 | NIH | 12/12/2023 | $433,715 |
| | 2024 | 2024 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R00DE028573 | Molecular regulatory mechanism of Zika virus-induced intracranial calcifications | 000 | 6 | NIH | 4/12/2024 | $248,999 |
| | 2024 | 2024 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01AT011905 | Sensing active movement of the self: reconsidering the cellular basis kinesthesia | 001 | 3 | NIH | 2/5/2024 | $495,465 |
| | 2024 | 2024 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01CA266059 | Single Visit Clinical Validation of ScreenFire, a Low-Cost HPV Test: Efficacy and Cost Effectiveness (SCALE) | 000 | 3 | NIH | 4/15/2024 | $503,441 |
| | 2024 | 2024 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01AI167939 | Chronic Antibody-Mediated Rejection of Kidney Allografts | 000 | 3 | NIH | 1/17/2024 | $581,726 |
| | 2024 | 2024 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | K08HL159236 | Developing a Donor-Candidate Risk Prediction System to Optimize Lung Allocation and Transplant Outcomes | 000 | 3 | NIH | 3/7/2024 | $150,753 |
| | 2024 | 2024 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | U01NS123658 | Optimization of CaMPARI for large-scale, cellular-resolution activity recording in freely-moving mice | 000 | 3 | NIH | 1/12/2024 | $243,956 |
| | 2024 | 2024 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | U01NS123658 | Optimization of CaMPARI for large-scale, cellular-resolution activity recording in freely-moving mice | 000 | 3 | NIH | 1/12/2024 | $455,974 |
| | 2024 | 2024 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01CA248048 | A novel determinant of prostate cancer growth | 001 | 4 | NIH | 4/16/2024 | $16,137 |
| | 2024 | 2024 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01CA248048 | A novel determinant of prostate cancer growth | 000 | 4 | NIH | 3/1/2024 | $290,488 |
| | 2024 | 2024 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01AI153173 | Uncovering aryl polyene biology to identify new drug targets in Gram-negative bacterial pathogens | 000 | 4 | NIH | 3/7/2024 | $362,250 |
| | 2024 | 2024 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01HL158007 | Mechanisms controlling the efficiency of hemostatic vitamin K-dependent protein activation | 000 | 4 | NIH | 3/20/2024 | $494,378 |
| | 2024 | 2024 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01AI153348 | HCMV GPCR functions during latency and reactivation | 000 | 4 | NIH | 2/7/2024 | $392,260 |
| | 2024 | 2024 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01AG070736 | CYCLE-AD: Randomized Controlled Trial to Assess the Efficacy of Indoor Cycling in Slowing Disease Progression in Healthy Older Persons at Genetic Risk for Alzheimer?s Disease | 000 | 4 | NIH | 1/9/2024 | $1,138,476 |
| | 2024 | 2024 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | K08AA028794 | Mechanisms of HIF1 alpha mediated dysregulated skeletal muscle proteostasis in alcoholic liver disease | 000 | 4 | NIH | 2/12/2024 | $179,129 |
| | 2024 | 2024 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01AI150931 | Manipulation of host factors that promote HCMV latency | 000 | 4 | NIH | 2/7/2024 | $426,209 |
| | 2024 | 2024 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01MH124530 | Iron Dysregulation and Neuropsychiatric Complications of HIV Across the Lifespan: Impact of Biologic Factors, Antiretroviral Therapy and Genetics | 000 | 4 | NIH | 12/18/2023 | $370,368 |
| | 2024 | 2024 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01CA257502 | Discovering the role of YES1 in triple negative breast cancer | 004 | 4 | NIH | 4/16/2024 | $3,782 |
| | 2024 | 2024 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01CA257502 | Discovering the role of YES1 in triple negative breast cancer | 003 | 4 | NIH | 4/16/2024 | $23,068 |
| | 2024 | 2024 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01CA257502 | Discovering the role of YES1 in triple negative breast cancer | 002 | 4 | NIH | 2/12/2024 | $0 |
| | 2024 | 2024 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01CA257502 | Discovering the role of YES1 in triple negative breast cancer | 001 | 4 | NIH | 1/5/2024 | $68,068 |
| | 2024 | 2024 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01CA257502 | Discovering the role of YES1 in triple negative breast cancer | 000 | 4 | NIH | 1/4/2024 | $415,201 |
| | 2024 | 2024 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | K23HL150279 | Novel Cardiac MRI-Based Predictors for Tetralogy of Fallot: Deformation, Kinematic, and Geometric Analyses | 000 | 4 | NIH | 1/15/2024 | $172,788 |
| | 2024 | 2024 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01AI160740 | Mechanisms of alloantibody production following renal transplantation | 000 | 4 | NIH | 1/17/2024 | $537,128 |
| | 2024 | 2024 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01HL155064 | TRPV4 Regulates Mechanosensitive Macrophage Functions in Lung Injury | 000 | 4 | NIH | 1/30/2024 | $382,925 |
| | 2024 | 2024 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01DK126772 | Unraveling strain-level variation in the induction of anti-inflammatory responses in the intestine | 000 | 4 | NIH | 12/27/2023 | $433,135 |
| | 2024 | 2024 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01EY032342 | Mechanisms of retinal degeneration in neuroinflammatory demyelinating diseases | 000 | 4 | NIH | 12/8/2023 | $402,500 |
| | 2024 | 2024 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01CA244958 | Mechanisms of nuclear Mcl-1 mediated chemoresistance | 001 | 4 | NIH | 4/17/2024 | $18,415 |
| | 2024 | 2024 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01CA244958 | Mechanisms of nuclear Mcl-1 mediated chemoresistance | 000 | 4 | NIH | 11/9/2023 | $331,459 |
| | 2024 | 2024 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01NS119178 | The role of the astrocyte immunoproteasome during chronic CNS autoimmunity | 001 | 4 | NIH | 4/25/2024 | $28,175 |
| | 2024 | 2024 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01NS119178 | The role of the astrocyte immunoproteasome during chronic CNS autoimmunity | 000 | 4 | NIH | 11/10/2023 | $362,250 |
| | 2024 | 2024 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01DK120830 | Per-Oral Pyloromyotomy (POP) in the treatment of medical refractory gastroparesis : A randomized, sham-controlled trial | 000 | 5 | NIH | 3/26/2024 | $253,575 |
| | 2024 | 2024 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01AG066627 | Early Stage Studies of a Novel Positive Allosteric Modulator of the Alpha1-Adrenergic Receptor to Treat Alzheimer's Disease | 000 | 5 | NIH | 3/15/2024 | $362,250 |
| | 2024 | 2024 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01AG067146 | Adipokines, Aging, and Alzheimers Disease | 000 | 5 | NIH | 4/19/2024 | $474,473 |
| | 2024 | 2024 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01AG066707 | Endophenotype Network-based Approaches to Prediction and Population-based Validation of in Silico Drug Repurposing for Alzheimer?s Disease | 000 | 5 | NIH | 1/18/2024 | $532,638 |
| | 2024 | 2024 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01AA027766 | The role of hippocampal neurogenesis in alcohol withdrawal seizure and cognition | 000 | 5 | NIH | 3/27/2024 | $444,782 |
| | 2024 | 2024 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01DK121689 | The role of acetogenic, methanogenic, and sulfate-reducing bacteria in oxalate metabolism and hyperoxaluria | 000 | 5 | NIH | 2/16/2024 | $406,618 |
| | 2024 | 2024 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | K08CA228039 | Complement in Paclitaxel-induced peripheral neuropathy | 000 | 5 | NIH | 1/30/2024 | $233,863 |
| | 2024 | 2024 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R37CA244613 | Exploiting Ecology and Evolution to Prevent Therapy Resistance in EGFR-Driven Lung Cancer | 001 | 5 | NIH | 4/17/2024 | $22,384 |
| | 2024 | 2024 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R37CA244613 | Exploiting Ecology and Evolution to Prevent Therapy Resistance in EGFR-Driven Lung Cancer | 000 | 5 | NIH | 11/29/2023 | $402,867 |
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