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Mummichog 3, aligning mass spectrometry data to biological networks - Neutral Loss

Award Number: U01CA235493
ORGANIZATION: NATIONAL CANCER INSTITUTE
OPDIV: NIH
AWARD CLASS: COOPERATIVE AGREEMENT
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 09/06/2018
PERIOD OF PERFORMANCE END DATE: 08/31/2023

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View Award Description

Mummichog 3, aligning mass spectrometry data to biological networks - Neutral Loss - PROJECT SUMMARY / ABSTRACT The mummichog software was initially published in 2013, as a computational approach to match patterns in metabolomics data to known biochemical networks, without the requirement of upfront metabolite identification. This approach enables rapid generation of biological hypotheses from untargeted data, and has gained considerable popularity, which also creates urgent needs to upgrade the software itself. This proposal aims to add a rich user interface, and better support of LC-MS, LCMS/ MS, IMS/MS and GC-MS. Furthermore, this work will make a conceptual leap to establish a framework of network alignment as a vehicle to interpret metabolomics data by integrating multiple layers of information. The new development will be integrated into XCMS Online and MetaboAnalyst, and will be made freely available as modular software tools.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2024 ( Subtotal = -$653 )
2024	2021	JACKSON LABORATORY	600 MAIN ST	BAR HARBOR	ME	04609	HANCOCK	USA	Trans-NIH Research Support	000	4	2/12/2024	NON-COMPETING CONTINUATION	-$442
2024	2021	JACKSON LABORATORY	600 MAIN ST	BAR HARBOR	ME	04609	HANCOCK	USA	Trans-NIH Research Support	001	4	2/12/2024	SUPPLEMENT FOR EXPANSION	-$211
														Subtotal = -$653

Issue Date FY: 2023 ( Subtotal = $0 )
2023	2021	JACKSON LABORATORY	600 MAIN ST	BAR HARBOR	ME	04609	HANCOCK	USA	Trans-NIH Research Support	000	4	3/7/2023	NON-COMPETING CONTINUATION	$0
														Subtotal = $0

Issue Date FY: 2022 ( Subtotal = $123,362 )
2022	2021	THE JACKSON LABORATORY	600 MAIN ST	BAR HARBOR	ME	04609	HANCOCK	USA	Trans-NIH Research Support	001	4	4/22/2022	NON-COMPETING CONTINUATION	$123,362
2022	2020	THE JACKSON LABORATORY	600 MAIN ST	BAR HARBOR	ME	04609	HANCOCK	USA	Trans-NIH Research Support	000	3	12/2/2021	CHANGE OF GRANTEE / TRAINING INSTITUTION / AWARDING INSTITUTION	$0
														Subtotal = $123,362

Issue Date FY: 2021 ( Subtotal = $558,063 )
2021	2021	THE JACKSON LABORATORY	600 MAIN ST	BAR HARBOR	ME	04609	HANCOCK	USA	Trans-NIH Research Support	007	4	9/28/2021	NON-COMPETING CONTINUATION	$173,000
2021	2021	THE JACKSON LABORATORY	600 MAIN ST	BAR HARBOR	ME	04609	HANCOCK	USA	Trans-NIH Research Support	004	3	9/8/2021	SUPPLEMENT FOR EXPANSION	-$110,203
2021	2021	THE JACKSON LABORATORY	600 MAIN ST	BAR HARBOR	ME	04609	HANCOCK	USA	Trans-NIH Research Support	003	3	9/3/2021	SUPPLEMENT FOR EXPANSION	$110,203
2021	2021	THE JACKSON LABORATORY	600 MAIN ST	BAR HARBOR	ME	04609	HANCOCK	USA	Trans-NIH Research Support	006	4	9/14/2021	SUPPLEMENT FOR EXPANSION	$110,203
2021	2021	THE JACKSON LABORATORY	600 MAIN ST	BAR HARBOR	ME	04609	HANCOCK	USA	Trans-NIH Research Support	002	4	9/1/2021	NON-COMPETING CONTINUATION	$164,657
2021	2021	THE JACKSON LABORATORY	600 MAIN ST	BAR HARBOR	ME	04609	HANCOCK	USA	Trans-NIH Research Support	005	4	9/10/2021	SUPPLEMENT FOR EXPANSION	$110,203
2021	2020	THE JACKSON LABORATORY	600 MAIN ST	BAR HARBOR	ME	04609	HANCOCK	USA	Trans-NIH Research Support	001	3	3/15/2021	CHANGE OF GRANTEE / TRAINING INSTITUTION / AWARDING INSTITUTION	$296,363
2021	2019	EMORY UNIVERSITY	201 DOWMAN DR	ATLANTA	GA	30322	DEKALB	USA	Trans-NIH Research Support	000	2	3/15/2021	NON-COMPETING CONTINUATION	-$296,363
														Subtotal = $558,063

Issue Date FY: 2020 ( Subtotal = $461,019 )
2020	2020	THE JACKSON LABORATORY	600 MAIN ST	BAR HARBOR	ME	04609	HANCOCK	USA	Trans-NIH Research Support	001	3	9/17/2020	CHANGE OF GRANTEE / TRAINING INSTITUTION / AWARDING INSTITUTION	$461,019
2020	2019	EMORY UNIVERSITY	201 DOWMAN DR	ATLANTA	GA	30322	DEKALB	USA	Trans-NIH Research Support	000	2	9/17/2020	NON-COMPETING CONTINUATION	$0
														Subtotal = $461,019

Issue Date FY: 2019 ( Subtotal = $406,485 )
2019	2019	EMORY UNIVERSITY	1599 CLIFTON RD.	ATLANTA	GA	30322	DEKALB	USA	Trans-NIH Research Support	000	2	8/30/2019	NON-COMPETING CONTINUATION	$406,485
														Subtotal = $406,485

Issue Date FY: 2018 ( Subtotal = $431,683 )
2018	2018	EMORY UNIVERSITY	1599 CLIFTON RD.	ATLANTA	GA	30322	DEKALB	USA	Trans-NIH Research Support	000	1	9/6/2018	NEW	$431,683
														Subtotal = $431,683

Grand Total All Awards = $1,979,959

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Mummichog 3, aligning mass spectrometry data to biological networks - Neutral Loss

Award Number: U01CA235493

ORGANIZATION: NATIONAL CANCER INSTITUTE

OPDIV: NIH

AWARD CLASS: COOPERATIVE AGREEMENT

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 09/06/2018

PERIOD OF PERFORMANCE END DATE: 08/31/2023

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