Thursday, February 19, 2026 2/19/2026

Quantitative Systemic Studies of Bacterial Physiology

Award Number: R35GM152133
ORGANIZATION: NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 03/01/2024
PERIOD OF PERFORMANCE END DATE: 02/28/2029

Group Awards By:

View Award Description

Quantitative Systemic Studies of Bacterial Physiology - Project Summary This research will significantly expand the PI’s unique research program in quantitative bacterial physiology from the exclusive focus on the model organism Escherichia coli during the past decade to a variety of species across the bacterial phylogeny, including Vibrio, Pseudomonas, Bacteroides, Mycobacterium, and Bacillus. Transcriptomic, proteomic, and metabolomic approaches will be applied to these bacterial species for a spectrum of conditions with emphasis on cementing absolute abundances of the measured quantities as well as the rate of synthesis and turnover. For each species investigated, we will replicate previous studies for E. coli to derive both coarse-grained phenomenological models as well as establish relation to molecular regulation. We will also develop methods for inter-species comparisons at the quantitative level. These studies will not only generate a vast amount of useful quantitative data and models for bacteria of


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2025 ( Subtotal = $605,017 )
2025	2025	UNIVERSITY OF CALIFORNIA, SAN DIEGO	9500 GILMAN DR	LA JOLLA	CA	92093	SAN DIEGO	USA	Biomedical Research and Research Training	001	2	2/20/2025	NON-COMPETING CONTINUATION	$544,515
2025	2025	UNIVERSITY OF CALIFORNIA, SAN DIEGO	9500 GILMAN DR	LA JOLLA	CA	92093	SAN DIEGO	USA	Biomedical Research and Research Training	002	2	8/14/2025	NON-COMPETING CONTINUATION	$60,502
2025	2024	UNIVERSITY OF CALIFORNIA, SAN DIEGO	9500 GILMAN DR	LA JOLLA	CA	92093	SAN DIEGO	USA	Biomedical Research and Research Training	000	1	11/27/2024	NEW	$0
														Subtotal = $605,017

Issue Date FY: 2024 ( Subtotal = $605,017 )
2024	2024	UNIVERSITY OF CALIFORNIA, SAN DIEGO	9500 GILMAN DR	LA JOLLA	CA	92093	SAN DIEGO	USA	Biomedical Research and Research Training	000	1	1/23/2024	NEW	$605,017
														Subtotal = $605,017

Grand Total All Awards = $1,210,034

Top

All Categories

About

Search

Reports

Data Submission

Award Information

Quantitative Systemic Studies of Bacterial Physiology

Award Number: R35GM152133

ORGANIZATION: NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 03/01/2024

PERIOD OF PERFORMANCE END DATE: 02/28/2029

Federal Websites

Department of Health & Human Services

HHS Operating Divisions

HHS Staff Divisions

Download A Document Viewer