Monday, June 30, 2025 6/30/2025

Workshop on Statistical Genetic Methods for Human Complex Traits

Award Number: R25MH019918
ORGANIZATION: NATIONAL INSTITUTE OF MENTAL HEALTH
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 09/30/1992
PERIOD OF PERFORMANCE END DATE: 06/30/2028

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Workshop on Statistical Genetic Methods for Human Complex Traits - PROJECT SUMMARY This proposal requests a further five years of funding to support the organization and delivery of in-person and virtual intensive training workshops focused on the development of skills in statistical, behavioral, and quantitative genetics that will advance the mission of NIMH. Four workshops will be in-person over one week and one will be virtual across two weeks. We also request funding to support the development of a website devoted to self-education of this material and that will greatly increase the reach of the workshop. The workshop and its associated website are targeted at post-doctoral trainees, graduate and medical students, and early career faculty currently conducting or planning to initiate research on the genetics of mental health. To balance the needs of investigators using a variety of methodologies, our in-person workshops will alternate between a focus on structural equation modeling of twin, family, multivariate, and developmental data (the “Latent Genetics Course”), and a workshop focusing on the analysis of measured genome variation including sequence data (the “Molecular Genetics Course”). The virtual course will cover both content areas with a slightly more introductory focus. The website will be a central hub for learning statistical genetics of all content types. It will be made up of video lectures, practicals, code, and relevant readings along with a forum, all organized by topic and cross-referenced. Through both didactics and hands-on experience, research scientists participating in the workshops will refine their research skills in genetic design and analysis. The workshop offers an innovative program designed to provide education in state-of-the-art genetic methodology important to fulfill the objectives of the current NIMH Strategic Plan. Although designed for training, the live (in-person and virtual) workshops share some characteristics of a scientific meeting. Participants are encouraged to discuss their current research, to bring copies of their data to work on directly while at the workshop, and to discuss and develop research plans. New collaborations are established to facilitate high quality research on existing data sets, and new research initiatives are strengthened by collaborations formed at the workshop. Its curriculum is continuously updated by world leaders in statistical, behavioral, and quantitative genetics and their applications to mental health. This workshop has historically been one of the most important gateways to behavioral, statistical, and quantitative genetics. It has logged ~3,000 registrations since its inception in 1987. A large proportion of authors of papers with keywords such as “GWAS” and “twin studies” have attended the workshop and many leaders in the field got their start at it. The proposed workshop formats (in-person, virtual, and online) represent a modernization of how content is delivered and have already born fruit in terms of increased reach and diversity.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2024 ( Subtotal = $172,802 )
2024	2024	THE REGENTS OF THE UNIVERSITY OF COLORADO	3100 MARINE ST	BOULDER	CO	80309	BOULDER	USA	Mental Health Research Grants	002	32	7/12/2024	NON-COMPETING CONTINUATION	$172,802
2024	2023	THE REGENTS OF THE UNIVERSITY OF COLORADO	3100 MARINE ST	BOULDER	CO	80309	BOULDER	USA	Mental Health Research Grants	001	31	6/17/2024	COMPETING CONTINUATION	$97,192
2024	2022	THE REGENTS OF THE UNIVERSITY OF COLORADO	3100 MARINE ST	BOULDER	CO	80309	BOULDER	USA	Mental Health Research Grants	000	30	6/17/2024	NON-COMPETING CONTINUATION	-$97,192
														Subtotal = $172,802

Issue Date FY: 2023 ( Subtotal = $215,995 )
2023	2023	REGENTS OF THE UNIVERSITY OF COLORADO, THE	3100 MARINE ST STE 481 572 UCB	BOULDER	CO	80309	BOULDER	USA	Mental Health Research Grants	001	31	3/31/2023	COMPETING CONTINUATION	$215,995
2023	2023	REGENTS OF THE UNIVERSITY OF COLORADO, THE	3100 MARINE ST STE 481 572 UCB	BOULDER	CO	80309	BOULDER	USA	Mental Health Research Grants	003	31	4/8/2023	COMPETING CONTINUATION	$0
2023	2022	REGENTS OF THE UNIVERSITY OF COLORADO, THE	3100 MARINE ST STE 481 572 UCB	BOULDER	CO	80309	BOULDER	USA	Mental Health Research Grants	000	30	3/29/2023	NON-COMPETING CONTINUATION	$0
2023	2022	REGENTS OF THE UNIVERSITY OF COLORADO, THE	3100 MARINE ST STE 481 572 UCB	BOULDER	CO	80309	BOULDER	USA	Mental Health Research Grants	002	30	4/7/2023	NON-COMPETING CONTINUATION	$0
														Subtotal = $215,995

Issue Date FY: 2022 ( Subtotal = $212,103 )
2022	2022	REGENTS OF THE UNIVERSITY OF COLORADO, THE	3100 MARINE ST STE 481 572 UCB	BOULDER	CO	80309	BOULDER	USA	Mental Health Research Grants	000	30	7/8/2022	NON-COMPETING CONTINUATION	$212,103
														Subtotal = $212,103

Issue Date FY: 2021 ( Subtotal = $213,244 )
2021	2021	REGENTS OF THE UNIVERSITY OF COLORADO, THE	3100 MARINE ST STE 481 572 UCB	BOULDER	CO	80309	BOULDER	USA	Mental Health Research Grants	000	29	7/7/2021	NON-COMPETING CONTINUATION	$213,244
														Subtotal = $213,244

Issue Date FY: 2020 ( Subtotal = $214,674 )
2020	2020	REGENTS OF THE UNIVERSITY OF COLORADO, THE	3100 MARINE ST STE 481 572 UCB	BOULDER	CO	80309	BOULDER	USA	Mental Health Research Grants	000	28	6/18/2020	NON-COMPETING CONTINUATION	$214,674
														Subtotal = $214,674

Issue Date FY: 2019 ( Subtotal = $215,957 )
2019	2019	REGENTS OF THE UNIVERSITY OF COLORADO, THE	3100 MARINE ST STE 481 572 UCB	BOULDER	CO	80309	BOULDER	USA	Mental Health Research Grants	002	27	6/21/2019	NON-COMPETING CONTINUATION	$215,957
2019	2018	REGENTS OF THE UNIVERSITY OF COLORADO, THE	3100 MARINE ST STE 481 572 UCB	BOULDER	CO	80309	BOULDER	USA	Mental Health Research Grants	001	26	11/20/2018	COMPETING CONTINUATION	$73,780
2019	2017	REGENTS OF THE UNIVERSITY OF COLORADO, THE	3100 MARINE ST STE 481 572 UCB	BOULDER	CO	80309	BOULDER	USA	Mental Health Research Grants	000	25	11/20/2018	NON-COMPETING CONTINUATION	-$73,780
														Subtotal = $215,957

Issue Date FY: 2018 ( Subtotal = $215,957 )
2018	2018	REGENTS OF THE UNIVERSITY OF COLORADO, THE	3100 MARINE ST., RM 479 572 UCB	BOULDER	CO	80303	BOULDER	USA	Mental Health Research Grants	000	26	4/4/2018	COMPETING CONTINUATION	$215,957
														Subtotal = $215,957

Issue Date FY: 2017 ( Subtotal = $195,428 )
2017	2017	REGENTS OF THE UNIVERSITY OF COLORADO, THE	3100 MARINE ST., RM 479 572 UCB	BOULDER	CO	80303	BOULDER	USA	Mental Health Research Grants	002	25	6/15/2017	NON-COMPETING CONTINUATION	$195,428
2017	2016	REGENTS OF THE UNIVERSITY OF COLORADO, THE	3100 MARINE ST., RM 479 572 UCB	BOULDER	CO	80303	BOULDER	USA	Mental Health Research Grants	001	24	12/12/2016	EXTENSION WITH OR WITHOUT FUNDS	$40,374
2017	2015	REGENTS OF THE UNIVERSITY OF COLORADO, THE	3100 MARINE ST., RM 479 572 UCB	BOULDER	CO	80303	BOULDER	USA	Mental Health Research Grants	000	23	12/12/2016	NON-COMPETING CONTINUATION	-$40,374
														Subtotal = $195,428

Issue Date FY: 2016 ( Subtotal = $195,428 )
2016	2016	UNIVERSITY OF COLORADO, OFFICE OF CONTRACTS & GRANTS	CAMPUS BOX B-19	BOULDER	CO	80309	BOULDER	USA	Mental Health Research Grants	000	24	6/10/2016	EXTENSION WITH OR WITHOUT FUNDS	$195,428
														Subtotal = $195,428

Issue Date FY: 2015 ( Subtotal = $195,428 )
2015	2015	UNIVERSITY OF COLORADO, OFFICE OF CONTRACTS & GRANTS	CAMPUS BOX B-19	BOULDER	CO	80309	BOULDER	USA	Mental Health Research Grants	000	23	6/19/2015	NON-COMPETING CONTINUATION	$195,428
														Subtotal = $195,428

Issue Date FY: 2014 ( Subtotal = $195,428 )
2014	2014	UNIVERSITY OF COLORADO, OFFICE OF CONTRACTS & GRANTS	CAMPUS BOX B-19	BOULDER	CO	80309	BOULDER	USA	Mental Health Research Grants	000	22	6/27/2014	NON-COMPETING CONTINUATION	$195,428
														Subtotal = $195,428

Issue Date FY: 2013 ( Subtotal = $195,428 )
2013	2013	UNIVERSITY OF COLORADO, OFFICE OF CONTRACTS & GRANTS	CAMPUS BOX B-19	BOULDER	CO	80309	BOULDER	USA	Mental Health Research Grants	000	21	7/1/2013	COMPETING CONTINUATION	$193,454
2013	2013	UNIVERSITY OF COLORADO, OFFICE OF CONTRACTS & GRANTS	CAMPUS BOX B-19	BOULDER	CO	80309	BOULDER	USA	Mental Health Research Grants	001	21	9/10/2013	COMPETING CONTINUATION	$1,974
														Subtotal = $195,428

Issue Date FY: 2012 ( Subtotal = $139,644 )
2012	2012	UNIVERSITY OF COLORADO, OFFICE OF CONTRACTS & GRANTS	CAMPUS BOX B-19	BOULDER	CO	80309	BOULDER	USA	Mental Health Research Grants	000	20	6/20/2012	NON-COMPETING CONTINUATION	$139,644
														Subtotal = $139,644

Issue Date FY: 2011 ( Subtotal = $145,567 )
2011	2011	UNIVERSITY OF COLORADO, OFFICE OF CONTRACTS & GRANTS	CAMPUS BOX B-19	BOULDER	CO	80309	BOULDER	USA	Mental Health Research Grants	000	19	6/29/2011	NON-COMPETING CONTINUATION	$145,567
														Subtotal = $145,567

Issue Date FY: 2010 ( Subtotal = $141,610 )
2010	2010	UNIVERSITY OF COLORADO, OFFICE OF CONTRACTS & GRANTS	CAMPUS BOX B-19	BOULDER	CO	80309	BOULDER	USA	Mental Health Research Grants	000	18	7/12/2010	NON-COMPETING CONTINUATION	$141,610
														Subtotal = $141,610

Issue Date FY: 2009 ( Subtotal = $139,862 )
2009	2009	UNIVERSITY OF COLORADO, OFFICE OF CONTRACTS & GRANTS	CAMPUS BOX B-19	BOULDER	CO	80309	BOULDER	USA	Mental Health Research Grants	000	17	7/10/2009	NON-COMPETING CONTINUATION	$139,862
														Subtotal = $139,862

Issue Date FY: 2008 ( Subtotal = $135,835 )
2008	2008	UNIVERSITY OF COLORADO, OFFICE OF CONTRACTS & GRANTS	CAMPUS BOX B-19	BOULDER	CO	80309	BOULDER	USA	Mental Health Research Grants	000	16	8/27/2008	COMPETING CONTINUATION	$135,835
														Subtotal = $135,835

Issue Date FY: 2007 ( Subtotal = $155,530 )
2007	2007	UNIVERSITY OF COLORADO, OFFICE OF CONTRACTS & GRANTS	CAMPUS BOX B-19	BOULDER	CO	80309	BOULDER	USA	Mental Health Research Grants	000	15	6/26/2007	NON-COMPETING CONTINUATION	$155,530
														Subtotal = $155,530

Issue Date FY: 2006 ( Subtotal = $155,507 )
2006	2006	UNIVERSITY OF COLORADO, OFFICE OF CONTRACTS & GRANTS	CAMPUS BOX B-19	BOULDER	CO	80309	BOULDER	USA	Mental Health Research Grants	000	14	7/18/2006	NON-COMPETING CONTINUATION	$155,507
														Subtotal = $155,507

Issue Date FY: 2005 ( Subtotal = $150,979 )
2005	2005	UNIVERSITY OF COLORADO, OFFICE OF CONTRACTS & GRANTS	CAMPUS BOX B-19	BOULDER	CO	80309	BOULDER	USA	Mental Health Research Grants	000	13	8/30/2005	NON-COMPETING CONTINUATION	$150,979
														Subtotal = $150,979

Grand Total All Awards = $4,353,957

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Workshop on Statistical Genetic Methods for Human Complex Traits

Award Number: R25MH019918

ORGANIZATION: NATIONAL INSTITUTE OF MENTAL HEALTH

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 09/30/1992

PERIOD OF PERFORMANCE END DATE: 06/30/2028

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