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A Randomized Trial to Prevent HIV Among Gay Couples

Award Number: R01MH110289
ORGANIZATION: NATIONAL INSTITUTE OF MENTAL HEALTH
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 09/20/2016
PERIOD OF PERFORMANCE END DATE: 07/31/2022

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A Randomized Trial to Prevent HIV Among Gay Couples - In the US, men who have sex with men (MSM) represent the largest proportion of AIDS deaths, people living with AIDS, and HIV incidence. While numerous prevention efforts targeting MSM have successfully reduced HIV incidence in the US, many men are not reached, including gay couples. Several epidemiological studies attribute high rates of new HIV infections to condomless anal sex within male primary partnerships, but few prevention interventions are available to address and reverse this trend. Several factors have recently changed the HIV prevention landscape, including advancements in biomedical strategies, an increased desire to develop interventions that can be scaled up efficiently and a need to develop cost-effective programing due to decreases in prevention dollars. Multi-session individual- and group-level in-person sexual risk reduction interventions for MSM were the gold standard for many years. Behavioral interventions have also been delivered via the internet, since they are convenient, able to reach large numbers of individuals and less labor intensive to implement, compared to interventions delivered via multiple in- person sessions. It is important to examine the optimal modes of providing prevention interventions in the context of this changing prevention landscape. The majority of prevention interventions targeting MSM are individual-focused. However, over the years, our research has identified unique prevention needs for gay couples that have not been sufficiently addressed in individual-focused interventions. For example, while most gay couples have agreements about sex with partners outside the relationship, many couples have difficulty negotiating their agreements, some have difficulty adhering to their agreements and those who break their agreements have difficulty disclosing the break to their partner; all of which could pose potential HIV risk for the couple. Our study team has led the field in examining relationship dynamics among gay couples. With a goal to develop a theory driven yet empirically-informed intervention, we have been studying the nuances of relationships and determining the HIV risk factors that either persist or change over time. Several years of longitudinal quantitative and qualitative studies, have yielded the evidence for an empirically- driven model that provides a foundational framework for the proposed intervention. Additionally, due to a dearth of prevention interventions for gay couples, there is little documented knowledge about the best modes of intervention delivery. Specifically, we do not know if it is efficacious for couples to participate in an intervention in-person or online. We also do not know if particular topics are best addressed using one of these modes or the other. To address these questions, we propose in an R01 application, to test the efficacy of our theory-based and empirically-driven HIV risk reduction intervention for gay male couples using a randomized controlled trial.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2023 ( Subtotal = -$121,632 )
2023	2020	SAN FRANCISCO STATE UNIVERSITY	1600 HOLLOWAY AVE BUILDING NAD ROOM 358C	SAN FRANCISCO	CA	94132	SAN FRANCISCO	USA	Mental Health Research Grants	000	5	7/27/2023	NON-COMPETING CONTINUATION	-$121,632
														Subtotal = -$121,632

Issue Date FY: 2020 ( Subtotal = $638,048 )
2020	2020	SAN FRANCISCO STATE UNIVERSITY	1600 HOLLOWAY AVE BUILDING NAD ROOM 358C	SAN FRANCISCO	CA	94132	SAN FRANCISCO	USA	Mental Health Research Grants	000	5	7/28/2020	NON-COMPETING CONTINUATION	$638,048
														Subtotal = $638,048

Issue Date FY: 2019 ( Subtotal = $821,640 )
2019	2019	SAN FRANCISCO STATE UNIVERSITY	1600 HOLLOWAY AVE BUILDING NAD ROOM 358C	SAN FRANCISCO	CA	94132	SAN FRANCISCO	USA	Mental Health Research Grants	000	4	7/23/2019	NON-COMPETING CONTINUATION	$821,640
														Subtotal = $821,640

Issue Date FY: 2018 ( Subtotal = $834,202 )
2018	2018	SAN FRANCISCO STATE UNIVERSITY	1600 HOLLOWAY AVE BUILDING NAD ROOM 358C	SAN FRANCISCO	CA	94132	SAN FRANCISCO	USA	Mental Health Research Grants	000	3	7/14/2018	NON-COMPETING CONTINUATION	$834,202
														Subtotal = $834,202

Issue Date FY: 2017 ( Subtotal = $1,024,380 )
2017	2017	SAN FRANCISCO STATE UNIVERSITY	1600 HOLLOWAY AVE BUILDING NAD ROOM 358C	SAN FRANCISCO	CA	94132	SAN FRANCISCO	USA	Mental Health Research Grants	004	1	8/4/2017	SUPPLEMENT FOR EXPANSION	-$465
2017	2017	SAN FRANCISCO STATE UNIVERSITY	1600 HOLLOWAY AVE BUILDING NAD ROOM 358C	SAN FRANCISCO	CA	94132	SAN FRANCISCO	USA	Mental Health Research Grants	002	2	7/20/2017	NON-COMPETING CONTINUATION	$805,666
2017	2017	SAN FRANCISCO STATE UNIVERSITY	1600 HOLLOWAY AVE BUILDING NAD ROOM 358C	SAN FRANCISCO	CA	94132	SAN FRANCISCO	USA	Mental Health Research Grants	003	1	7/26/2017	SUPPLEMENT FOR EXPANSION	$0
2017	2017	SAN FRANCISCO STATE UNIVERSITY	1600 HOLLOWAY AVE BUILDING NAD ROOM 358C	SAN FRANCISCO	CA	94132	SAN FRANCISCO	USA	Mental Health Research Grants	001	1	6/29/2017	SUPPLEMENT FOR EXPANSION	$22,516
2017	2017	SAN FRANCISCO STATE UNIVERSITY	1600 HOLLOWAY AVE BUILDING NAD ROOM 358C	SAN FRANCISCO	CA	94132	SAN FRANCISCO	USA	Mental Health Research Grants	005	2	9/15/2017	NON-COMPETING CONTINUATION	$46,094
2017	2017	SAN FRANCISCO STATE UNIVERSITY	1600 HOLLOWAY AVE BUILDING NAD ROOM 358C	SAN FRANCISCO	CA	94132	SAN FRANCISCO	USA	Mental Health Research Grants	000	1	5/12/2017	SUPPLEMENT FOR EXPANSION	$150,569
														Subtotal = $1,024,380

Issue Date FY: 2016 ( Subtotal = $800,916 )
2016	2016	SAN FRANCISCO STATE UNIV	1600 HOLLOWAY AVENUE	SAN FRANCISCO	CA	94132	SAN FRANCISCO	USA	Mental Health Research Grants	000	1	9/20/2016	NEW	$800,916
														Subtotal = $800,916

Grand Total All Awards = $3,997,554

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A Randomized Trial to Prevent HIV Among Gay Couples

Award Number: R01MH110289

ORGANIZATION: NATIONAL INSTITUTE OF MENTAL HEALTH

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 09/20/2016

PERIOD OF PERFORMANCE END DATE: 07/31/2022

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