Wednesday, February 18, 2026 2/18/2026

Simultaneous Microwave and MR Imaging for Improved Diagnosis of Breast Abnormalities

Award Number: R01CA240760
ORGANIZATION: NATIONAL CANCER INSTITUTE
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 02/15/2020
PERIOD OF PERFORMANCE END DATE: 02/28/2027

Group Awards By:

View Award Description

Simultaneous Microwave and MR Imaging for Improved Diagnosis of Breast Abnormalities - PROJECT SUMMARY/ABSTRACT This Academic-Industry Partnership, AIP, proposal (PAR-18-009) will develop and evaluate an innovative multi-modality breast imaging platform that performs simultaneous Microwave and Magnetic Resonance Imaging (sMMRI). It incorporates a multiple-principal-investigator (multi-PI) research plan and AIP governance structure that leverages expertise from Dartmouth, Dartmouth-Hitchcock, and Quality Electrodynamics (QED) in biomedical engineering, MRI and microwave physics, computational inversion and estimation, and breast radiology. Industry partner QED will apply its extensive experience in design and implementation of specialized MRI coils that will be fully integrated and compatible with Dartmouth’s microwave imaging (MI) electronics and in-bore antenna array. To date, we have demonstrated technical feasibility of sMMRI and have realized a prototype that has delivered the first successful clinical breast exams. While potential promise of sMMRI has been suggested, especially in terms of acquiring quantitatively-accurate spatial maps of tissue electrical properties (i.e. permittivity and conductivity), further technical innovations are needed and more experience with sMMRI, both technically and clinically, is required to develop the technology sufficiently for a full clinical evaluation. To advance and optimize sMMRI of the breast while also increasing our understanding of its clinical potential, we propose to (1) develop and integrate MRI (receive) coils with MI antenna arrays to optimize MRI and MI image quality, and breast coverage during an sMMRI clinical breast exam, (2) estimate breast tissue electrical properties from sMMRI data by encoding MRI anatomical priors into the 3D reconstruction process, and (3) complete phantom and clinical breast imaging experiments with sMMRI to evaluate and optimize the proposed technical developments, and to conduct a clinical study in women with undiagnosed breast abnormalities to test the hypothesis that sMMRI improves the specificity of breast MR alone. If the studies we propose are successful, we will have realized an innovative multi-modality breast imaging platform that is ready for involvement in larger statistically-powered clinical studies of its diagnostic performance in the future.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2026 ( Subtotal = $0 )
2026	2024	TRUSTEES OF DARTMOUTH COLLEGE	7 LEBANON ST	HANOVER	NH	03755	GRAFTON	USA	Cancer Detection and Diagnosis Research	000	5	2/9/2026	NON-COMPETING CONTINUATION	$0
														Subtotal = $0

Issue Date FY: 2024 ( Subtotal = $555,556 )
2024	2024	TRUSTEES OF DARTMOUTH COLLEGE	7 LEBANON ST	HANOVER	NH	03755	GRAFTON	USA	Cancer Detection and Diagnosis Research	001	5	4/17/2024	NON-COMPETING CONTINUATION	$29,241
2024	2024	TRUSTEES OF DARTMOUTH COLLEGE	7 LEBANON ST	HANOVER	NH	03755	GRAFTON	USA	Cancer Detection and Diagnosis Research	000	5	2/14/2024	NON-COMPETING CONTINUATION	$526,315
														Subtotal = $555,556

Issue Date FY: 2023 ( Subtotal = $588,388 )
2023	2023	TRUSTEES OF DARTMOUTH COLLEGE	7 LEBANON ST	HANOVER	NH	03755	GRAFTON	USA	Cancer Detection and Diagnosis Research	000	4	2/13/2023	NON-COMPETING CONTINUATION	$588,388
														Subtotal = $588,388

Issue Date FY: 2022 ( Subtotal = $581,228 )
2022	2022	TRUSTEES OF DARTMOUTH COLLEGE	6001 PARKHURST HALL STE 207	HANOVER	NH	03755	GRAFTON	USA	Cancer Detection and Diagnosis Research	000	3	2/9/2022	NON-COMPETING CONTINUATION	$533,778
2022	2022	TRUSTEES OF DARTMOUTH COLLEGE	7 LEBANON ST	HANOVER	NH	03755	GRAFTON	USA	Cancer Detection and Diagnosis Research	001	3	5/11/2022	NON-COMPETING CONTINUATION	$47,450
														Subtotal = $581,228

Issue Date FY: 2021 ( Subtotal = $610,382 )
2021	2021	TRUSTEES OF DARTMOUTH COLLEGE	1 HINMAN DARTMOUTH COLLEGE	HANOVER	NH	03755	GRAFTON	USA	Cancer Detection and Diagnosis Research	000	2	2/2/2021	NON-COMPETING CONTINUATION	$610,382
														Subtotal = $610,382

Issue Date FY: 2020 ( Subtotal = $641,864 )
2020	2020	TRUSTEES OF DARTMOUTH COLLEGE	1 HINMAN DARTMOUTH COLLEGE	HANOVER	NH	03755	GRAFTON	USA	Cancer Detection and Diagnosis Research	000	1	2/14/2020	NEW	$641,864
														Subtotal = $641,864

Grand Total All Awards = $2,977,418

Top

All Categories

About

Search

Reports

Data Submission

Award Information

Simultaneous Microwave and MR Imaging for Improved Diagnosis of Breast Abnormalities

Award Number: R01CA240760

ORGANIZATION: NATIONAL CANCER INSTITUTE

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 02/15/2020

PERIOD OF PERFORMANCE END DATE: 02/28/2027

Federal Websites

Department of Health & Human Services

HHS Operating Divisions

HHS Staff Divisions

Download A Document Viewer