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Dual-Process Models of Alcohol Use in Late Adolescence

Award Number: K08AA024794
ORGANIZATION: NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: TRAINING/TRAINEESHIP
PERIOD OF PERFORMANCE START DATE: 05/10/2017
PERIOD OF PERFORMANCE END DATE: 08/31/2023

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Dual-Process Models of Alcohol Use in Late Adolescence - DESCRIPTION (provided by applicant): This Mentored Clinical Scientist Research Development Award (K08) will enable the applicant to develop expertise designing and implementing studies using performance-based tasks as a methodological tool for investigating etiological processes that are not easily accessible via introspection. Alcohol is the most commonly used drug in adolescence, with higher levels of drinking being robustly associated with cannabis use (the second most used drug) and externalizing and internalizing problems. Dual-process models explain heterogeneity and co-morbidity of alcohol use by postulating individual differences in motivation and cognitive control as risk factors for problematic drinking Different theoretical perspectives have emerged; some construe motivation as individual differences in reinforcement sensitivity, others as drug-specific memory associations. Motivational and cognitive control risk factors have been shown to predict externalizing and internalizing psychopathology, and hence dual-process models can elucidate who is at risk for drinking, and why drinking frequently co-occurs with other drug use and externalizing/internalizing problems. This project will be the first to concurrently test alternatie conceptualizations of motivation in dual-process models, and to examine the multi- dimensional structure of cognitive control in dual-process models. A better understanding of specific mechanisms in the development of drinking can inform our theoretical understanding of addictions, and potentially lead to interventions that target idiosyncratic etiological mechanisms. Training involves original data collection; 150 18-20 year olds are proposed to be sampled from a larger NIAAA funded project examining the development of drinking milestones. A battery of performance-based tasks will be administered to the sub- sample upon completion of participation in the larger study; tasks will measure different facets of motivation (reinforcement sensitivity, drug specific memory associations) and cognitive control (set-shifting, inhibition, working memory capacity). Web-based survey methods will be used to provide a short-term prospective test of dual-process models as applied to: alcohol and cannabis use/problem use, and symptoms of externalizing and internalizing psychopathology. The association of alcohol involvement with cannabis use, and externalizing and internalizing symptoms is expected to be attenuated after accounting for shared etiological mechanisms. This research will lead to subsequent R01 grant applications involving: 1) different pathways to the initiation of drinking, 2 the emergence of alcohol and cannabis use disorders in late-adolescence/young adulthood, and 3) transdiagnostic etiological models of alcoholism and psychopathology. This K08 will train the applicant for an independent research career in the field of addictions by expanding the breadth and depth of my programmatic line of research.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2024 ( Subtotal = -$380 )
2024	2021	UNIVERSITY OF RHODE ISLAND	75 LOWER COLLEGE RD RM 103	KINGSTON	RI	02881	WASHINGTON	USA	Alcohol Research Programs	000	6	2/12/2024	NON-COMPETING CONTINUATION	-$380
														Subtotal = -$380

Issue Date FY: 2023 ( Subtotal = $0 )
2023	2021	UNIVERSITY OF RHODE ISLAND	75 LOWER COLLEGE	KINGSTON	RI	02881	WASHINGTON	USA	Alcohol Research Programs	000	6	4/18/2023	NON-COMPETING CONTINUATION	$0
														Subtotal = $0

Issue Date FY: 2021 ( Subtotal = $194,508 )
2021	2021	UNIVERSITY OF RHODE ISLAND	75 LOWER COLLEGE	KINGSTON	RI	02881	WASHINGTON	USA	Alcohol Research Programs	002	6	4/13/2021	NON-COMPETING CONTINUATION	$194,508
2021	2020	UNIVERSITY OF RHODE ISLAND	75 LOWER COLLEGE	KINGSTON	RI	02881	WASHINGTON	USA	Alcohol Research Programs	004	5	5/6/2021	CHANGE OF GRANTEE / TRAINING INSTITUTION / AWARDING INSTITUTION	$5,767
2021	2020	UNIVERSITY OF RHODE ISLAND	75 LOWER COLLEGE	KINGSTON	RI	02881	WASHINGTON	USA	Alcohol Research Programs	001	5	3/9/2021	CHANGE OF GRANTEE / TRAINING INSTITUTION / AWARDING INSTITUTION	$194,508
2021	2020	BROWN UNIVERSITY IN PROVIDENCE IN THE STATE OF RHODE ISLAND AND PROVIDENCE PLANTATIONS	1 PROSPECT ST	PROVIDENCE	RI	02912	PROVIDENCE	USA	Alcohol Research Programs	000	4	3/9/2021	NON-COMPETING CONTINUATION	-$194,508
2021	2019	BROWN UNIVERSITY	1 PROSPECT ST	PROVIDENCE	RI	02912	PROVIDENCE	USA	Alcohol Research Programs	003	3	5/6/2021	NON-COMPETING CONTINUATION	-$5,767
														Subtotal = $194,508

Issue Date FY: 2020 ( Subtotal = $194,508 )
2020	2020	BROWN UNIVERSITY IN PROVIDENCE IN THE STATE OF RHODE ISLAND AND PROVIDENCE PLANTATIONS	1 PROSPECT ST	PROVIDENCE	RI	02912	PROVIDENCE	USA	Alcohol Research Programs	000	4	5/4/2020	NON-COMPETING CONTINUATION	$194,508
														Subtotal = $194,508

Issue Date FY: 2019 ( Subtotal = $194,508 )
2019	2019	BROWN UNIVERSITY IN PROVIDENCE IN THE STATE OF RHODE ISLAND AND PROVIDENCE PLANTATIONS	1 PROSPECT ST	PROVIDENCE	RI	02912	PROVIDENCE	USA	Alcohol Research Programs	000	3	4/15/2019	NON-COMPETING CONTINUATION	$194,508
														Subtotal = $194,508

Issue Date FY: 2018 ( Subtotal = $201,687 )
2018	2018	BROWN UNIVERSITY IN PROVIDENCE IN THE STATE OF RHODE ISLAND AND PROVIDENCE PLANTATIONS	1 PROSPECT ST	PROVIDENCE	RI	02912	PROVIDENCE	USA	Alcohol Research Programs	001	2	5/1/2018	NON-COMPETING CONTINUATION	$194,508
2018	2017	BROWN UNIVERSITY IN PROVIDENCE IN THE STATE OF RHODE ISLAND AND PROVIDENCE PLANTATIONS	1 PROSPECT ST	PROVIDENCE	RI	02912	PROVIDENCE	USA	Alcohol Research Programs	000	1	12/20/2017	NEW	$7,179
														Subtotal = $201,687

Issue Date FY: 2017 ( Subtotal = $187,329 )
2017	2017	BROWN UNIVERSITY IN PROVIDENCE IN THE STATE OF RHODE ISLAND AND PROVIDENCE PLANTATIONS	1 PROSPECT ST	PROVIDENCE	RI	02912	PROVIDENCE	USA	Alcohol Research Programs	000	1	5/9/2017	NEW	$187,329
														Subtotal = $187,329

Grand Total All Awards = $972,160

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Dual-Process Models of Alcohol Use in Late Adolescence

Award Number: K08AA024794

ORGANIZATION: NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: TRAINING/TRAINEESHIP

PERIOD OF PERFORMANCE START DATE: 05/10/2017

PERIOD OF PERFORMANCE END DATE: 08/31/2023

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