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National Centralized Repository for Alzheimer's Disease and Related Dementias (NCRAD)

Award Number: U24AG021886
ORGANIZATION: NATIONAL INSTITUTE ON AGING
OPDIV: NIH
AWARD CLASS: COOPERATIVE AGREEMENT
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

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PROJECT SUMMARY/ABSTRACT The US National Plan for AD (National Alzheimer's Project Act, NAPA) has the ambitious goal of preventing and effectively treating Alzheimer’s disease (AD) by 2025 through the support of innovative research focused on AD etiology, early detection, and therapeutics. The National Centralized Repository for Alzheimer’s Disease and Related Dementias (NCRAD) is an NIA-funded Cooperative Agreement that serves as the primary resource for sample sharing for all NIA-funded Alzheimer’s disease and related dementias (ADRD) studies. This application is in response to a request by NIA to continue the support for NCRAD (RFA-AG-21-005). Over the past 30 years, NCRAD has exceeded its goals for sample storage and sample distribution, and thereby significantly facilitated ADRD research progress. Over the next five years, NCRAD will work closely with NIA and other national efforts in ADRD research to advance genomic and biomarker efforts aimed at identifying those at greatest risk for ADRD and to delay and prevent ADRD. To achieve these key goals, NCRAD will pursue the following specific aims: Aim 1: Provide a state-of-the-art central biospecimen repository for all NIA-funded dementia studies. 1.1 Provide study-specific biospecimen management. 1.2 Ensure comprehensive specimen quality. 1.3 Receive and expand ADRD-related cell lines for distribution to the research community. Aim 2: Facilitate and foster sample sharing to all qualified investigators. 2.1 Maximize the value of samples at NCRAD. 2.2 Develop user-friendly approaches to promote and review NCRAD resources. 2.3 Distribute samples to (approved) researchers.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2024 ( Subtotal = $0 )
2024	2023	TRUSTEES OF INDIANA UNIVERSITY	980 INDIANA AVE RM 2232	INDIANAPOLIS	IN	46202	MARION	USA	Aging Research	000	22	1/29/2024	NON-COMPETING CONTINUATION	$0
														Subtotal = $0

Issue Date FY: 2023 ( Subtotal = $16,309,533 )
2023	2023	TRUSTEES OF INDIANA UNIVERSITY	980 INDIANA AVE RM 2232	INDIANAPOLIS	IN	46202	MARION	USA	Aging Research	002	22	6/30/2023	NON-COMPETING CONTINUATION	$6,053,040
2023	2023	TRUSTEES OF INDIANA UNIVERSITY	980 INDIANA AVE RM 2232	INDIANAPOLIS	IN	46202	MARION	USA	Aging Research	003	22	8/22/2023	SUPPLEMENT FOR EXPANSION	$10,257,187
2023	2022	TRUSTEES OF INDIANA UNIVERSITY	980 INDIANA AVE RM 2232	INDIANAPOLIS	IN	46202	MARION	USA	Aging Research	001	21	1/23/2023	NON-COMPETING CONTINUATION	$0
2023	2020	TRUSTEES OF INDIANA UNIVERSITY	980 INDIANA AVE RM 2232	INDIANAPOLIS	IN	46202	MARION	USA	Aging Research	000	19	11/21/2022	NON-COMPETING CONTINUATION	-$694
														Subtotal = $16,309,533

Issue Date FY: 2022 ( Subtotal = $10,431,057 )
2022	2022	TRUSTEES OF INDIANA UNIVERSITY	980 INDIANA AVE RM 2232	INDIANAPOLIS	IN	46202	MARION	USA	Aging Research	001	20	2/24/2022	SUPPLEMENT FOR EXPANSION	$1,148,501
2022	2022	TRUSTEES OF INDIANA UNIVERSITY	980 INDIANA AVE RM 2232	INDIANAPOLIS	IN	46202	MARION	USA	Aging Research	003	21	5/26/2022	SUPPLEMENT FOR EXPANSION	$384,149
2022	2022	TRUSTEES OF INDIANA UNIVERSITY	980 INDIANA AVE RM 2232	INDIANAPOLIS	IN	46202	MARION	USA	Aging Research	000	20	12/16/2021	SUPPLEMENT FOR EXPANSION	$396,250
2022	2022	TRUSTEES OF INDIANA UNIVERSITY	980 INDIANA AVE RM 2232	INDIANAPOLIS	IN	46202	MARION	USA	Aging Research	004	21	5/27/2022	SUPPLEMENT FOR EXPANSION	$2,387,113
2022	2022	TRUSTEES OF INDIANA UNIVERSITY	980 INDIANA AVE RM 2232	INDIANAPOLIS	IN	46202	MARION	USA	Aging Research	002	21	5/19/2022	NON-COMPETING CONTINUATION	$6,115,044
														Subtotal = $10,431,057

Issue Date FY: 2021 ( Subtotal = $6,574,330 )
2021	2021	TRUSTEES OF INDIANA UNIVERSITY	980 INDIANA AVE RM 2232	INDIANAPOLIS	IN	46202	MARION	USA	Aging Research	001	20	5/12/2021	COMPETING CONTINUATION	$6,178,080
2021	2021	TRUSTEES OF INDIANA UNIVERSITY	980 INDIANA AVE RM 2232	INDIANAPOLIS	IN	46202	MARION	USA	Aging Research	004	20	9/7/2021	COMPETING CONTINUATION	$0
2021	2021	TRUSTEES OF INDIANA UNIVERSITY	980 INDIANA AVE RM 2232	INDIANAPOLIS	IN	46202	MARION	USA	Aging Research	002	20	8/13/2021	SUPPLEMENT FOR EXPANSION	$396,250
2021	2020	TRUSTEES OF INDIANA UNIVERSITY	980 INDIANA AVE RM 2232	INDIANAPOLIS	IN	46202	MARION	USA	Aging Research	003	19	9/7/2021	NON-COMPETING CONTINUATION	$0
2021	2020	TRUSTEES OF INDIANA UNIVERSITY	980 INDIANA AVE RM 2232	INDIANAPOLIS	IN	46202	MARION	USA	Aging Research	000	19	4/28/2021	NON-COMPETING CONTINUATION	$0
														Subtotal = $6,574,330

Issue Date FY: 2020 ( Subtotal = $5,205,087 )
2020	2020	TRUSTEES OF INDIANA UNIVERSITY	980 INDIANA AVE RM 2232	INDIANAPOLIS	IN	46202	MARION	USA	Aging Research	001	19	5/8/2020	NON-COMPETING CONTINUATION	$5,205,087
2020	2014	TRUSTEES OF INDIANA UNIVERSITY	980 INDIANA AVE RM 2232	INDIANAPOLIS	IN	46202	MARION	USA	Aging Research	000	13	10/1/2019	SUPPLEMENT FOR EXPANSION	$0
														Subtotal = $5,205,087

Issue Date FY: 2019 ( Subtotal = $11,163,442 )
2019	2019	TRUSTEES OF INDIANA UNIVERSITY	980 INDIANA AVE RM 2232	INDIANAPOLIS	IN	46202	MARION	USA	Aging Research	003	18	5/22/2019	SUPPLEMENT FOR EXPANSION	$4,435,780
2019	2019	TRUSTEES OF INDIANA UNIVERSITY	980 INDIANA AVE RM 2232	INDIANAPOLIS	IN	46202	MARION	USA	Aging Research	002	18	5/21/2019	SUPPLEMENT FOR EXPANSION	$1,442,000
2019	2019	TRUSTEES OF INDIANA UNIVERSITY	980 INDIANA AVE RM 2232	INDIANAPOLIS	IN	46202	MARION	USA	Aging Research	001	18	5/2/2019	NON-COMPETING CONTINUATION	$5,285,662
2019	2018	TRUSTEES OF INDIANA UNIVERSITY	980 INDIANA AVE RM 2232	INDIANAPOLIS	IN	46202	MARION	USA	Aging Research	000	17	3/15/2019	NON-COMPETING CONTINUATION	$0
														Subtotal = $11,163,442

Issue Date FY: 2018 ( Subtotal = $5,352,415 )
2018	2018	TRUSTEES OF INDIANA UNIVERSITY	980 INDIANA AVE RM 2232	INDIANAPOLIS	IN	46202	MARION	USA	Aging Research	001	17	6/28/2018	SUPPLEMENT FOR EXPANSION	$4,000,002
2018	2018	TRUSTEES OF INDIANA UNIVERSITY	980 INDIANA AVE RM 2232	INDIANAPOLIS	IN	46202	MARION	USA	Aging Research	000	17	6/22/2018	NON-COMPETING CONTINUATION	$1,352,413
														Subtotal = $5,352,415

Issue Date FY: 2017 ( Subtotal = $1,368,628 )
2017	2017	TRUSTEES OF INDIANA UNIVERSITY	980 INDIANA AVE RM 2232	INDIANAPOLIS	IN	46202	MARION	USA	Aging Research	003	16	7/15/2017	NON-COMPETING CONTINUATION	$1,368,628
2017	2016	TRUSTEES OF INDIANA UNIVERSITY	980 INDIANA AVE RM 2232	INDIANAPOLIS	IN	46202	MARION	USA	Aging Research	002	15	1/13/2017	COMPETING CONTINUATION	$1,703,350
2017	2015	TRUSTEES OF INDIANA UNIVERSITY	980 INDIANA AVE RM 2232	INDIANAPOLIS	IN	46202	MARION	USA	Aging Research	000	14	1/13/2017	NON-COMPETING CONTINUATION	-$884,889
2017	2014	TRUSTEES OF INDIANA UNIVERSITY	980 INDIANA AVE RM 2232	INDIANAPOLIS	IN	46202	MARION	USA	Aging Research	001	13	1/13/2017	SUPPLEMENT FOR EXPANSION	-$818,461
														Subtotal = $1,368,628

Issue Date FY: 2016 ( Subtotal = $1,529,760 )
2016	2016	INDIANA UNIVERSITY, BLOOMINGTON	509 EAST 3RD STREET	BLOOMINGTON	IN	47405	MONROE	USA	Aging Research	002	15	9/16/2016	SUPPLEMENT FOR EXPANSION	$156,000
2016	2016	INDIANA UNIVERSITY, BLOOMINGTON	509 EAST 3RD STREET	BLOOMINGTON	IN	47405	MONROE	USA	Aging Research	000	15	9/12/2016	COMPETING CONTINUATION	$1,373,760
2016	2015	INDIANA UNIVERSITY, BLOOMINGTON	509 EAST 3RD STREET	BLOOMINGTON	IN	47405	MONROE	USA	Aging Research	001	14	9/12/2016	NON-COMPETING CONTINUATION	$0
														Subtotal = $1,529,760

Issue Date FY: 2015 ( Subtotal = $884,889 )
2015	2015	INDIANA UNIVERSITY, BLOOMINGTON	509 EAST 3RD STREET	BLOOMINGTON	IN	47405	MONROE	USA	Aging Research	000	14	7/13/2015	NON-COMPETING CONTINUATION	$884,889
														Subtotal = $884,889

Issue Date FY: 2014 ( Subtotal = $2,858,892 )
2014	2014	INDIANA UNIVERSITY, BLOOMINGTON	509 EAST 3RD STREET	BLOOMINGTON	IN	47405	MONROE	USA	Aging Research	000	13	6/20/2014	NON-COMPETING CONTINUATION	$927,002
2014	2014	INDIANA UNIVERSITY, BLOOMINGTON	509 EAST 3RD STREET	BLOOMINGTON	IN	47405	MONROE	USA	Aging Research	001	13	8/21/2014	SUPPLEMENT FOR EXPANSION	$1,931,890
														Subtotal = $2,858,892

Issue Date FY: 2013 ( Subtotal = $905,725 )
2013	2013	INDIANA UNIVERSITY, BLOOMINGTON	509 EAST 3RD STREET	BLOOMINGTON	IN	47405	MONROE	USA	Aging Research	000	12	6/20/2013	NON-COMPETING CONTINUATION	$905,725
														Subtotal = $905,725

Issue Date FY: 2012 ( Subtotal = $1,115,867 )
2012	2012	INDIANA UNIVERSITY, BLOOMINGTON	509 EAST 3RD STREET	BLOOMINGTON	IN	47405	MONROE	USA	Aging Research	001	11	9/5/2012	SUPPLEMENT FOR EXPANSION	$155,992
2012	2012	INDIANA UNIVERSITY, BLOOMINGTON	509 EAST 3RD STREET	BLOOMINGTON	IN	47405	MONROE	USA	Aging Research	000	11	6/22/2012	NON-COMPETING CONTINUATION	$959,875
														Subtotal = $1,115,867

Issue Date FY: 2011 ( Subtotal = $945,143 ) (Continued on the next page)
Grand Total All Awards = $72,342,105

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National Centralized Repository for Alzheimer's Disease and Related Dementias (NCRAD)

Award Number: U24AG021886

ORGANIZATION: NATIONAL INSTITUTE ON AGING

OPDIV: NIH

AWARD CLASS: COOPERATIVE AGREEMENT

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

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