The Molecular and Environmental Toxicology Training Program (MET-TP) involves 32 trainers that have
outstanding training records and well-funded research programs. These trainers cover a variety of research
areas such as developmental toxicology, predictive toxicology, structural biology, high throughput toxicology,
stem cell toxicology, mammalian genetics, molecular biology and biochemistry. Predoctoral trainees are
typically supported for a period of two years and can perform molecular toxicology research in over a dozen
unique departments housed in multiple colleges on the UW campus. Postdoctoral trainees are also supported
for two years and have the same access to the trainer pool as predocs, but are required to submit an Individual
NRSA application in their first six months. The selection of trainees and oversight of the grant will be carried
out by the Training Grant Leadership (TGL) which consists of the director and two deputy directors. In
addition, four subcommittees monitor student progress, curriculum, recruitment and trainee input. The MET-
TP will be reviewed by an Internal review process from eth School of Medicine and Public Health (SMPH) and
External Advisory Board composed of nationally recognized toxicologists. This proposal seeks continued
support for eight predoctoral and three postdoctoral positions and requests and additional position for a
predoctoral trainee from an underrepresented minority. All predoctoral trainees take a MET-TP core curriculum
comprised of courses in basic mechanistic toxicology, the environment and human disease, research ethics
and career development. They are also required to attend a weekly toxicology research seminar, and
complete additional courses required by their Trainer. Pre- and postdoctoral trainees will also be mentored in
grant writing, ethics, managing techniques and teaching and will complete two courses in Responsible Conduct
of Research. Finally each trainee will be trained as lifelong learners through the participation in multiple
continuing education courses and in their role developing a scientific symposia related to environmental health.
Predoctoral trainee progress is monitored by Research Advisory Committees for each trainee and by the TGL.
Postdoctoral training is facilitated by appointment of a Postdoctoral Career Advisory Committee (two faculty
mentors in addition to a trainer) that will recommend selected didactic continuing education courses,
collaborations and professional development credits. The recruitment of minorities to the Program is given
high priority and is facilitated by a NIEHS-funded Summer Minority Research Program for undergraduates.
Upon completion of the training program, graduates usually undertake a period of postdoctoral training, or
assume responsible career positions in toxicology in academic, governmental, or other public or private
research institutions, or industrial laboratories.