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FROM BENCH TO BEDSIDE: MOLECULAR STORIES OF RESEARCH-BASED HEALTH CARE

Award Number: R25RR022749
ORGANIZATION: NATIONAL CENTER FOR RESEARCH RESOURCES
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 09/26/2005
PERIOD OF PERFORMANCE END DATE: 06/30/2012

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FROM BENCH TO BEDSIDE: MOLECULAR STORIES OF RESEARCH-BASED HEALTH CARE - The goal of this project is to develop Inquiry-based Curriculum Units (ICUs) that present basic concepts of molecular structure in the form of "molecular stories" of research-based health care. These ICUs will be developed by a team of science educators composed of staff of the MSOE Center for BioMolecular Modeling (CBM), a veteran teacher with curriculum writing experience, a science education researcher who will develop assessment instruments to accompany each ICU, and high school science teachers who are familiar with the ICU topic as a result of an immersive professional development experience. The professional development program begins with an established summer course, Genes, Schemes and Molecular Machines, which updates the teachers' content knowledge of basic concepts of molecular structure and function. This summer course is followed by a week-long Modeling Workshop in which teachers select an interesting human disease, and explore the molecular basis of the disease while creating physical models of the affected proteins. During the ensuing academic year, teachers will organize a SMART Team (Students Modeling A Research Topic) in their schools and interact directly with a basic or clinical researcher at a local university to create a physical model of the protein that serves as a drug target for the disease. In the summer following this multi-component, in-depth exploration of the molecular basis of a disease and its treatment, the teachers will participate as members of the ICU Design Team. Each ICU will follow a standard inquiry-driven format that provides opportunities for students to discover basic concepts of molecular structure through active, hands-on modeling activities. This knowledge is then applied to the clinical situation in a way that emphasizes critical thinking skills. The ICUs that are developed in this project will be broadly disseminated to other teachers in presentations and workshops given by CBM staff and the participating teachers, to students through a Protein Modeling event of the Wisconsin Science Olympiad , in an outreach program to students of the Milwaukee Boys & Girls Club, and to adult learners in a series of public lectures hosted by our local Discovery World Museum. The common theme of each ICU is the critical role played by NIH-supported basic and clinical research in the development of new molecular approaches to the treatment of human diseases.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2011 ( Subtotal = $0 )
2011	2009	MILWAUKEE SCHOOL OF ENGINEERING	1025 NORTH MILWAUKEE STREET	MILWAUKEE	WI	53202	MILWAUKEE	USA	National Center for Research Resources	000	5	9/20/2011	NON-COMPETING CONTINUATION	$0
														Subtotal = $0

Issue Date FY: 2010 ( Subtotal = $247,157 )
2010	2010	MILWAUKEE SCHOOL OF ENGINEERING	1025 NORTH MILWAUKEE STREET	MILWAUKEE	WI	53202	MILWAUKEE	USA	National Center for Research Resources	000	5	9/17/2010	SUPPLEMENT FOR EXPANSION	$247,157
														Subtotal = $247,157

Issue Date FY: 2009 ( Subtotal = $249,403 )
2009	2009	MILWAUKEE SCHOOL OF ENGINEERING	1025 NORTH MILWAUKEE STREET	MILWAUKEE	WI	53202	MILWAUKEE	USA	National Center for Research Resources	000	5	6/30/2009	NON-COMPETING CONTINUATION	$249,403
														Subtotal = $249,403

Issue Date FY: 2008 ( Subtotal = $249,403 )
2008	2008	MILWAUKEE SCHOOL OF ENGINEERING	1025 NORTH MILWAUKEE STREET	MILWAUKEE	WI	53202	MILWAUKEE	USA	National Center for Research Resources	000	4	8/9/2008	NON-COMPETING CONTINUATION	$249,403
														Subtotal = $249,403

Issue Date FY: 2007 ( Subtotal = $254,491 )
2007	2007	MILWAUKEE SCHOOL OF ENGINEERING	1025 NORTH MILWAUKEE STREET	MILWAUKEE	WI	53202	MILWAUKEE	USA	National Center for Research Resources	000	3	8/3/2007	NON-COMPETING CONTINUATION	$254,491
														Subtotal = $254,491

Issue Date FY: 2006 ( Subtotal = $262,483 )
2006	2006	MILWAUKEE SCHOOL OF ENGINEERING	1025 NORTH MILWAUKEE STREET	MILWAUKEE	WI	53202	MILWAUKEE	USA	National Center for Research Resources	000	2	7/26/2006	NON-COMPETING CONTINUATION	$262,483
														Subtotal = $262,483

Issue Date FY: 2005 ( Subtotal = $268,164 )
2005	2005	MILWAUKEE SCHOOL OF ENGINEERING	1025 NORTH MILWAUKEE STREET	MILWAUKEE	WI	53202	MILWAUKEE	USA	National Center for Research Resources	000	1	9/26/2005	NEW	$268,164
														Subtotal = $268,164

Grand Total All Awards = $1,531,101

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FROM BENCH TO BEDSIDE: MOLECULAR STORIES OF RESEARCH-BASED HEALTH CARE

Award Number: R25RR022749

ORGANIZATION: NATIONAL CENTER FOR RESEARCH RESOURCES

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 09/26/2005

PERIOD OF PERFORMANCE END DATE: 06/30/2012

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