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Effects of Exercise Training Intensity on Fitness and Insulin Sensitivity in African Americans

Award Number: R03DK105297
ORGANIZATION: NATIONAL INSTITUTE OF DIABETES & DIGESTIVE & KIDNEY DISEASES
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

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¿ DESCRIPTION: African Americans have a much greater risk of type 2 diabetes compared to Caucasians in the United States. Similarly, recent evidence has emerged that fitness level, a major risk factor for type 2 diabetes also tends to be lower in African Americans. Many scientific studies have shown that exercise training has a beneficial impact on fitness levels and a variety of other type 2 diabetes risk factors such as the reduction of glucose/insulin levels, and body fat Importantly, studies performed in mostly Caucasian populations suggest that exercise training at a vigorous intensity may promote greater improvements in type 2 diabetes risk factors compared to moderate intensity exercise, which may suggest that it has greater promise in reducing type 2 diabetes risk. However, few exercise training studies compare the health benefits of different exercise training programs (such as exercise intensity) in African Americans, which is clinically important due to their greater type 2 diabetes risk, and that fact that they are less likely to meet public health recommendations for physical activity compared to their Caucasian counterparts. The goal of proposed study is to evaluate the effects of 6 months of moderate versus vigorous exercise training in obese African Americans. The study will focus on the change in fitness levels, however, we will also collect information on the change in insulin sensitivity, skeletal muscle markers (associated with fitness or insulin sensitivity), body fat levels, quality of life, and enjoyment of exercise. This study will provide valuable information on what type of exercise training will offer the greatest improvement in T2DM risk factors in African Americans and potentially the prevention of type 2 diabetes.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2021 ( Subtotal = -$15,848 )
2021	2018	EAST CAROLINA UNIVERSITY	1000 E 5TH ST	GREENVILLE	NC	27858	PITT	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	000	3	6/10/2021	NON-COMPETING CONTINUATION	-$15,848
														Subtotal = -$15,848

Issue Date FY: 2020 ( Subtotal = $0 )
2020	2018	EAST CAROLINA UNIVERSITY	1000 E 5TH ST	GREENVILLE	NC	27858	PITT	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	000	3	5/22/2020	NON-COMPETING CONTINUATION	$0
														Subtotal = $0

Issue Date FY: 2019 ( Subtotal = $0 )
2019	2018	EAST CAROLINA UNIVERSITY	1000 E 5TH ST	GREENVILLE	NC	27858	PITT	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	000	3	10/23/2018	NON-COMPETING CONTINUATION	$0
														Subtotal = $0

Issue Date FY: 2018 ( Subtotal = $184,375 )
2018	2018	EAST CAROLINA UNIVERSITY	1000 E 5TH ST	GREENVILLE	NC	27858	PITT	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	000	3	4/20/2018	NON-COMPETING CONTINUATION	$184,375
														Subtotal = $184,375

Issue Date FY: 2017 ( Subtotal = $184,375 )
2017	2017	EAST CAROLINA UNIVERSITY	1000 E 5TH ST	GREENVILLE	NC	27858	PITT	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	000	2	4/11/2017	NON-COMPETING CONTINUATION	$165,937
2017	2017	EAST CAROLINA UNIVERSITY	1000 E 5TH ST	GREENVILLE	NC	27858	PITT	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	001	2	6/23/2017	NON-COMPETING CONTINUATION	$18,438
														Subtotal = $184,375

Issue Date FY: 2016 ( Subtotal = $184,375 )
2016	2016	EAST CAROLINA UNIVERSITY	2200 S Charles Boulevard	GREENVILLE	NC	27858	PITT	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	000	1	4/19/2016	NEW	$184,375
														Subtotal = $184,375

Grand Total All Awards = $537,277

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Effects of Exercise Training Intensity on Fitness and Insulin Sensitivity in African Americans

Award Number: R03DK105297

ORGANIZATION: NATIONAL INSTITUTE OF DIABETES & DIGESTIVE & KIDNEY DISEASES

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

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