Friday, April 19, 2024 4/19/2024

Predicting Sleep, Smoking and Lung Health Disparities in at-risk Black African American Adults

Award Number: R01MD012734
ORGANIZATION: NATIONAL CENTER ON MINORITY HEALTH AND HEALTH DISPARITIES
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

Group Awards By Issue Date FY or Funding FY:

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Project Abstract Black/African American's (BAAs) are more likely to report insufficient sleep duration (<7 hours) and other sleep deficiencies (e.g., poor sleep quality), and to have advanced Chronic Obstructive Pulmonary Disease (COPD), than Non-Hispanic Whites (NHW) with similar smoking behaviors. Insufficient sleep has been related to: (1) continued cigarette smoking, and (2) impaired lung function in healthy adults. Thus, sleep deficiencies could be an “upstream” primary and/or secondary prevention target to address racial disparities in tobacco use and COPD onset and progression. Not known are the multi-level (i.e., individual, social and environmental) factors that predict insufficient sleep duration and other sleep deficiencies in BAA's across time, and the extent to which sleep deficiencies predict poorer health outcomes such as continued tobacco use and worsening lung function in BAA smokers. To address these knowledge gaps, we will conduct a multi-disciplinary 5-year prospective observational study that will enroll and follow a representative sample of 480 BAAs who are current smokers, are aged >39 years, and who have prodromal (GOLD stage 0) or early stage COPD (GOLD stage 1-2). We will prospectively examine key individual, social, and environmental variables in concert with objectively measured sleep metrics, tobacco use, inflammatory markers, and lung function in this health disparate sample. Longitudinal mixed, classification and regression, and structural equation modeling will define key predictors (and future intervention targets) of sleep deficiencies in BAA's as well as delineate the extent to which insufficient sleep (and other sleep deficiencies) interact with tobacco use and inflammation markers to predict worsening lung function. The expected outcome from this work is to define multi-level phenotypes of risk for sleep deficiencies, continued tobacco use, and worsening lung function in this health disparate population of mid-life BAA smokers. This work directly aligns with, and advances the NIMHD mission to conduct and support research in minority health and health disparities.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2024 ( Subtotal = $0 )
2024	2022	TEMPLE UNIVERSITY-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION	1805 N BROAD ST	PHILADELPHIA	PA	19122	PHILADELPHIA	USA	Minority Health and Health Disparities Research	000	5	4/3/2024	NON-COMPETING CONTINUATION	$0
														Subtotal = $0

Issue Date FY: 2022 ( Subtotal = $612,677 )
2022	2022	TEMPLE UNIVERSITY-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION	1801 N BROAD ST	PHILADELPHIA	PA	19122	PHILADELPHIA	USA	Minority Health and Health Disparities Research	000	5	11/9/2021	NON-COMPETING CONTINUATION	$551,409
2022	2022	TEMPLE UNIVERSITY-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION	1801 N BROAD ST	PHILADELPHIA	PA	19122	PHILADELPHIA	USA	Minority Health and Health Disparities Research	001	5	4/25/2022	NON-COMPETING CONTINUATION	$61,268
														Subtotal = $612,677

Issue Date FY: 2021 ( Subtotal = $612,677 )
2021	2021	TEMPLE UNIVERSITY-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION	1801 N BROAD ST	PHILADELPHIA	PA	19122	PHILADELPHIA	USA	Minority Health and Health Disparities Research	001	4	3/11/2021	NON-COMPETING CONTINUATION	$61,268
2021	2021	TEMPLE UNIVERSITY-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION	1801 N BROAD ST	PHILADELPHIA	PA	19122	PHILADELPHIA	USA	Minority Health and Health Disparities Research	000	4	11/23/2020	NON-COMPETING CONTINUATION	$551,409
														Subtotal = $612,677

Issue Date FY: 2020 ( Subtotal = $612,677 )
2020	2020	TEMPLE UNIVERSITY-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION	1801 N BROAD ST	PHILADELPHIA	PA	19122	PHILADELPHIA	USA	Minority Health and Health Disparities Research	001	3	1/3/2020	NON-COMPETING CONTINUATION	$61,268
2020	2020	TEMPLE UNIVERSITY-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION	1801 N BROAD ST	PHILADELPHIA	PA	19122	PHILADELPHIA	USA	Minority Health and Health Disparities Research	000	3	10/30/2019	NON-COMPETING CONTINUATION	$551,409
														Subtotal = $612,677

Issue Date FY: 2019 ( Subtotal = $670,746 )
2019	2019	TEMPLE UNIVERSITY-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION	1801 N BROAD ST	PHILADELPHIA	PA	19122	PHILADELPHIA	USA	Minority Health and Health Disparities Research	000	2	11/15/2018	NON-COMPETING CONTINUATION	$670,746
														Subtotal = $670,746

Issue Date FY: 2018 ( Subtotal = $728,933 )
2018	2018	TEMPLE UNIVERSITY-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION	1801 N BROAD ST	PHILADELPHIA	PA	19122	PHILADELPHIA	USA	Minority Health and Health Disparities Research	000	1	3/23/2018	NEW	$656,040
2018	2018	TEMPLE UNIVERSITY-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION	1801 N BROAD ST	PHILADELPHIA	PA	19122	PHILADELPHIA	USA	Minority Health and Health Disparities Research	001	1	6/22/2018	NEW	$72,893
														Subtotal = $728,933

Grand Total All Awards = $3,237,710

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Predicting Sleep, Smoking and Lung Health Disparities in at-risk Black African American Adults

Award Number: R01MD012734

ORGANIZATION: NATIONAL CENTER ON MINORITY HEALTH AND HEALTH DISPARITIES

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

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