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A high-performance unshielded wearable brain-computer interface based on microfabricated total-field OPMs

Award Number: R01EB027004
ORGANIZATION: NATIONAL INSTITUTE Of BIOMEDICAL IMAGING & BIOENGINEERING
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

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Project Summary: The broad, long-term goal of this project is to develop a wearable high performance MEG system that can operate without external shielding that will lead to Advances in Human Neuroscience and transformative advances in our understanding of the Human Brain ‘in Action and in Context’, which are currently unachievable via imaging technologies in live persons. There are two specific aims: Aim 1 is a Small- scale, proof-of-concept development of uMEG Sensors to validate a novel non-invasive contactless uncooled unshielded magnetic sensor system based on total-field optically-pumped magnetometers (tOPM). Aim 2 is a small-scale human study to generate preliminary results with the uMEG system. Here, we will design and validate a closed-loop uMEG-based brain-computer interface (BCI) system in healthy adults. The proof-of- principle prototype system will be the first flexible array of total-field optically-pumped magnetometers (OPMs) that has the potential to enable a truly wearable MEG system for behaviorally active human neuroimaging that allows for movement in space/place during imaging in more natural environments while maintaining high resolution. This system will lead to next generation high-performance non-invasive closed-loop wearable neural interfaces that can be used to control prosthetics, computers and other assistive and therapeutic devices to study, diagnose, repair, augment, or restore cognitive-motor capabilities after brain injury or neurological disease.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2023 ( Subtotal = -$153,226 )
2023	2019	UNIVERSITY OF HOUSTON SYSTEM	4300 MARTIN LUTHER KING BLVD	HOUSTON	TX	77204	HARRIS	USA	Discovery and Applied Research for Technological Innovations to Improve Human Health	000	2	1/19/2023	NON-COMPETING CONTINUATION	-$153,226
														Subtotal = -$153,226

Issue Date FY: 2021 ( Subtotal = $0 )
2021	2019	UNIVERSITY OF HOUSTON SYSTEM	4800 W CALHOUN ST STE 316	HOUSTON	TX	77004	HARRIS	USA	Discovery and Applied Research for Technological Innovations to Improve Human Health	000	2	9/23/2021	NON-COMPETING CONTINUATION	$0
														Subtotal = $0

Issue Date FY: 2019 ( Subtotal = $426,693 )
2019	2019	UNIVERSITY OF HOUSTON SYSTEM	4800 W CALHOUN ST STE 316	HOUSTON	TX	77004	HARRIS	USA	Discovery and Applied Research for Technological Innovations to Improve Human Health	000	2	7/31/2019	NON-COMPETING CONTINUATION	$426,693
														Subtotal = $426,693

Issue Date FY: 2018 ( Subtotal = $450,407 )
2018	2018	UNIVERSITY OF HOUSTON SYSTEM	4800 W CALHOUN ST STE 316	HOUSTON	TX	77004	HARRIS	USA	Discovery and Applied Research for Technological Innovations to Improve Human Health	000	1	9/20/2018	NEW	$450,407
														Subtotal = $450,407

Grand Total All Awards = $723,874

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A high-performance unshielded wearable brain-computer interface based on microfabricated total-field OPMs

Award Number: R01EB027004

ORGANIZATION: NATIONAL INSTITUTE Of BIOMEDICAL IMAGING & BIOENGINEERING

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

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