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Comprehensive Biology: Exploiting the Yeast Genome

Award Number: P41GM103533
ORGANIZATION: NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

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Project Summary Since its inception, the Yeast Resource Center has focused on understanding how genome sequence relates to protein function. The Center began just as budding yeast became the first eukaryote to have its genome sequence completed, and we proposed to use an array of technologies to interpret this sequence. In this application, we undertake novel challenges, centered on understanding how variation in proteins affects their levels, modification, function and structure. We will develop new technologies in three areas: 1) Perturbing and sensing changes to complex pathways; 2) Protein detection and quantitation by mass spectrometry; and 3) Higher order protein structure. These technologies will be driven by ten closely integrated Driving Biomedical Projects. Yeast remains an unparalleled experimental system to develop, test and refine these technologies. As the technologies mature, we will extend their application to higher eukaryotes through internal projects and external collaborations. Furthermore, we make our technologies available as they become robust, through broad collaboration and a well-established track record of dissemination and training.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2022 ( Subtotal = -$84,595 )
2022	2021	UNIVERSITY OF WASHINGTON	4333 BROOKLYN AVE NE	SEATTLE	WA	98195	KING	USA	Biomedical Research and Research Training	000	25	8/28/2022	NON-COMPETING CONTINUATION	-$84,595
														Subtotal = -$84,595

Issue Date FY: 2021 ( Subtotal = $1,850,727 )
2021	2021	UNIVERSITY OF WASHINGTON	4333 BROOKLYN AVE NE	SEATTLE	WA	98195	KING	USA	Biomedical Research and Research Training	000	25	4/7/2021	NON-COMPETING CONTINUATION	$1,850,727
														Subtotal = $1,850,727

Issue Date FY: 2020 ( Subtotal = $1,870,727 )
2020	2020	UNIVERSITY OF WASHINGTON	4333 BROOKLYN AVE NE	SEATTLE	WA	98195	KING	USA	Biomedical Research and Research Training	000	24	4/8/2020	NON-COMPETING CONTINUATION	$1,870,727
														Subtotal = $1,870,727

Issue Date FY: 2019 ( Subtotal = $1,867,528 )
2019	2019	UNIVERSITY OF WASHINGTON	4333 BROOKLYN AVE NE	SEATTLE	WA	98195	KING	USA	Biomedical Research and Research Training	000	23	3/26/2019	NON-COMPETING CONTINUATION	$1,867,528
														Subtotal = $1,867,528

Issue Date FY: 2018 ( Subtotal = $2,477,228 )
2018	2018	UNIVERSITY OF WASHINGTON	4333 BROOKLYN AVE NE	SEATTLE	WA	98195	KING	USA	Biomedical Research and Research Training	004	22	3/8/2018	NON-COMPETING CONTINUATION	$1,662,775
2018	2018	UNIVERSITY OF WASHINGTON	4333 BROOKLYN AVE NE	SEATTLE	WA	98195	KING	USA	Biomedical Research and Research Training	005	22	4/25/2018	NON-COMPETING CONTINUATION	$184,753
2018	2018	UNIVERSITY OF WASHINGTON	4333 BROOKLYN AVE NE	SEATTLE	WA	98195	KING	USA	Biomedical Research and Research Training	006	22	8/1/2018	SUPPLEMENT FOR EXPANSION	$629,700
2018	2017	UNIVERSITY OF WASHINGTON	4333 BROOKLYN AVE NE	SEATTLE	WA	98195	KING	USA	Biomedical Research and Research Training	002	21	1/12/2018	COMPETING CONTINUATION	$8,257
2018	2017	UNIVERSITY OF WASHINGTON	4333 BROOKLYN AVE NE	SEATTLE	WA	98195	KING	USA	Biomedical Research and Research Training	003	20	1/12/2018	SUPPLEMENT FOR EXPANSION	-$8,257
2018	2016	UNIVERSITY OF WASHINGTON	4333 BROOKLYN AVE NE	SEATTLE	WA	98195	KING	USA	Biomedical Research and Research Training	001	20	1/12/2018	SUPPLEMENT FOR EXPANSION	$1
2018	2015	UNIVERSITY OF WASHINGTON	4333 BROOKLYN AVE NE	SEATTLE	WA	98195	KING	USA	Biomedical Research and Research Training	000	20	1/12/2018	NON-COMPETING CONTINUATION	-$1
														Subtotal = $2,477,228

Issue Date FY: 2017 ( Subtotal = $2,801,599 )
2017	2017	UNIVERSITY OF WASHINGTON	4333 BROOKLYN AVE NE	SEATTLE	WA	98195	KING	USA	Biomedical Research and Research Training	001	21	6/20/2017	COMPETING CONTINUATION	$2,330,696
2017	2017	UNIVERSITY OF WASHINGTON	4333 BROOKLYN AVE NE	SEATTLE	WA	98195	KING	USA	Biomedical Research and Research Training	000	20	2/15/2017	SUPPLEMENT FOR EXPANSION	$470,903
														Subtotal = $2,801,599

Issue Date FY: 2016 ( Subtotal = $936,446 )
2016	2016	UNIVERSITY OF WASHINGTON	3917 UNIVERSITY WAY NE	SEATTLE	WA	98105	KING	USA	Biomedical Research and Research Training	000	20	7/25/2016	SUPPLEMENT FOR EXPANSION	$936,446
														Subtotal = $936,446

Issue Date FY: 2015 ( Subtotal = $1,872,434 )
2015	2015	UNIVERSITY OF WASHINGTON	3917 UNIVERSITY WAY NE	SEATTLE	WA	98105	KING	USA	Biomedical Research and Research Training	000	20	7/14/2015	NON-COMPETING CONTINUATION	$1,872,434
														Subtotal = $1,872,434

Issue Date FY: 2014 ( Subtotal = $2,217,058 )
2014	2014	UNIVERSITY OF WASHINGTON	3917 UNIVERSITY WAY NE	SEATTLE	WA	98105	KING	USA	Biomedical Research and Research Training	000	19	7/1/2014	NON-COMPETING CONTINUATION	$2,217,058
														Subtotal = $2,217,058

Issue Date FY: 2013 ( Subtotal = $2,373,007 )
2013	2013	UNIVERSITY OF WASHINGTON	3917 UNIVERSITY WAY NE	SEATTLE	WA	98105	KING	USA	Biomedical Research and Research Training	000	18	7/9/2013	NON-COMPETING CONTINUATION	$2,373,007
														Subtotal = $2,373,007

Issue Date FY: 2012 ( Subtotal = $2,432,751 )
2012	2012	UNIVERSITY OF WASHINGTON	3917 UNIVERSITY WAY NE	SEATTLE	WA	98105	KING	USA	Biomedical Research and Research Training	000	17	7/11/2012	CHANGE OF GRANTEE / TRAINING INSTITUTION / AWARDING INSTITUTION	$2,078,690
2012	2012	UNIVERSITY OF WASHINGTON	3917 UNIVERSITY WAY NE	SEATTLE	WA	98105	KING	USA	Biomedical Research and Research Training	001	17	8/9/2012	SUPPLEMENT FOR EXPANSION	$354,061
														Subtotal = $2,432,751

Grand Total All Awards = $20,614,910

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Comprehensive Biology: Exploiting the Yeast Genome

Award Number: P41GM103533

ORGANIZATION: NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

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