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Resource-based Center for the study of the joint microenvironment in rheumatology (Overall Application)

Award Number: P30AR073761
ORGANIZATION: NATIONAL INSTITUTE OF ARTHRITIS & MUSCULOSKELETAL & SKIN DISEASES
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

Group Awards By Issue Date FY or Funding FY:

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OVERALL ABSTRACT We will establish a Rheumatic Diseases Research Resource Center at the University of California, San Diego (UCSD). The theme of our Microenvironment in Arthritis Resource MARC (MARC) is to facilitate translational research focused on the joint microenvironment in arthritis. Limited knowledge of in situ joint biology and pathogenic mechanisms in rheumatic diseases has prevented development of novel biomarkers and therapies that target cellular interactions within joint structures. The MARC will address this gap by stimulating interest in the joint microenvironment among a large interdisciplinary group of well-funded scientists from multiple institutions in San Diego. The goal of the MARC is to provide the San Diego scientific community with a comprehensive local framework to plan, perform and analyze a large variety of joint microenvironment studies using invasive and non-invasive technology and foster novel, collaborative, and interdisciplinary arthritis- relevant research. The first two Aims of the Center are to facilitate studies on tissue microenvironment by providing access to (Aim 1) cutting-edge joint imaging technology and approaches to isolate single cells and tissue from joints and to (Aim 2) a dedicated computational service focusing on integration of diverse multi- dimensional datasets. Aim 3 is to lower the barrier for new investigators to enter the field and to foster collaboration between rheumatic disease-focused scientists across San Diego. This will be accomplished via an Enrichment Program, which includes vouchers for core services, pilot and feasibility grant funding, and creation of a new arthritis seminar series and a regional arthritis-focused symposium to stimulate collaboration. The San Diego science community has a deeply rooted combination of creativity, dynamism, collaborative attitude and focus on translation. Thus, our Center will be uniquely positioned to facilitate the novel science that will be transformative for the diagnosis and treatment of rheumatic diseases.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2023 ( Subtotal = $0 )
2023	2022	UNIVERSITY OF CALIFORNIA, SAN DIEGO	9500 GILMAN DRIVE	LA JOLLA	CA	92093	SAN DIEGO	USA	Arthritis, Musculoskeletal and Skin Diseases Research	002	5	9/28/2023	NON-COMPETING CONTINUATION	$0
2023	2022	UNIVERSITY OF CALIFORNIA, SAN DIEGO	9500 GILMAN DRIVE	LA JOLLA	CA	92093	SAN DIEGO	USA	Arthritis, Musculoskeletal and Skin Diseases Research	001	5	8/7/2023	NON-COMPETING CONTINUATION	$0
2023	2022	UNIVERSITY OF CALIFORNIA, SAN DIEGO	9500 GILMAN DR	LA JOLLA	CA	92093	SAN DIEGO	USA	Arthritis, Musculoskeletal and Skin Diseases Research	000	5	1/9/2023	NON-COMPETING CONTINUATION	$0
														Subtotal = $0

Issue Date FY: 2022 ( Subtotal = $770,182 )
2022	2022	UNIVERSITY OF CALIFORNIA, SAN DIEGO	9500 GILMAN DR	LA JOLLA	CA	92093	SAN DIEGO	USA	Arthritis, Musculoskeletal and Skin Diseases Research	002	5	8/29/2022	NON-COMPETING CONTINUATION	$770,182
2022	2021	UNIVERSITY OF CALIFORNIA, SAN DIEGO	9500 GILMAN DR	LA JOLLA	CA	92093	SAN DIEGO	USA	Arthritis, Musculoskeletal and Skin Diseases Research	001	4	7/18/2022	NON-COMPETING CONTINUATION	$0
2022	2020	UNIVERSITY OF CALIFORNIA, SAN DIEGO	9500 GILMAN DR	LA JOLLA	CA	92093	SAN DIEGO	USA	Arthritis, Musculoskeletal and Skin Diseases Research	000	3	2/24/2022	NON-COMPETING CONTINUATION	$0
														Subtotal = $770,182

Issue Date FY: 2021 ( Subtotal = $775,357 )
2021	2021	UNIVERSITY OF CALIFORNIA, SAN DIEGO	9500 GILMAN DR	LA JOLLA	CA	92093	SAN DIEGO	USA	Arthritis, Musculoskeletal and Skin Diseases Research	002	4	8/20/2021	NON-COMPETING CONTINUATION	$775,357
2021	2020	UNIVERSITY OF CALIFORNIA, SAN DIEGO	9500 GILMAN DR	LA JOLLA	CA	92093	SAN DIEGO	USA	Arthritis, Musculoskeletal and Skin Diseases Research	000	3	11/4/2020	NON-COMPETING CONTINUATION	$0
2021	2020	UNIVERSITY OF CALIFORNIA, SAN DIEGO	9500 GILMAN DR	LA JOLLA	CA	92093	SAN DIEGO	USA	Arthritis, Musculoskeletal and Skin Diseases Research	001	3	7/22/2021	NON-COMPETING CONTINUATION	$0
														Subtotal = $775,357

Issue Date FY: 2020 ( Subtotal = $778,323 )
2020	2020	UNIVERSITY OF CALIFORNIA, SAN DIEGO	9500 GILMAN DR	LA JOLLA	CA	92093	SAN DIEGO	USA	Arthritis, Musculoskeletal and Skin Diseases Research	001	3	9/3/2020	NON-COMPETING CONTINUATION	$778,323
2020	2019	UNIVERSITY OF CALIFORNIA, SAN DIEGO	9500 GILMAN DR	LA JOLLA	CA	92093	SAN DIEGO	USA	Arthritis, Musculoskeletal and Skin Diseases Research	000	2	1/10/2020	NON-COMPETING CONTINUATION	$0
														Subtotal = $778,323

Issue Date FY: 2019 ( Subtotal = $782,778 )
2019	2019	UNIVERSITY OF CALIFORNIA, SAN DIEGO	9500 GILMAN DR DEPT 621	LA JOLLA	CA	92093	SAN DIEGO	USA	Arthritis, Musculoskeletal and Skin Diseases Research	001	2	9/10/2019	NON-COMPETING CONTINUATION	$0
2019	2019	UNIVERSITY OF CALIFORNIA, SAN DIEGO	9500 GILMAN DR DEPT 621	LA JOLLA	CA	92093	SAN DIEGO	USA	Arthritis, Musculoskeletal and Skin Diseases Research	000	2	9/3/2019	NON-COMPETING CONTINUATION	$782,778
														Subtotal = $782,778

Issue Date FY: 2018 ( Subtotal = $785,417 )
2018	2018	UNIVERSITY OF CALIFORNIA, SAN DIEGO	9500 GILMAN DR DEPT 621	LA JOLLA	CA	92093	SAN DIEGO	USA	Arthritis, Musculoskeletal and Skin Diseases Research	000	1	8/20/2018	NEW	$785,417
														Subtotal = $785,417

Grand Total All Awards = $3,892,057

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Resource-based Center for the study of the joint microenvironment in rheumatology (Overall Application)

Award Number: P30AR073761

ORGANIZATION: NATIONAL INSTITUTE OF ARTHRITIS & MUSCULOSKELETAL & SKIN DISEASES

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

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