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Effects of Alcohol and Tobacco Co-use on Momentary Subjective Cannabis Effects: Risks for Increasingly Hazardous Cannabis Use

Award Number: F31DA056066
ORGANIZATION: NATIONAL INSTITUTE ON DRUG ABUSE
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: FELLOWSHIP/SCHOLARSHIP/STUDENT LOANS

Group Awards By Issue Date FY or Funding FY:

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PROJECT SUMMARY The rates of cannabis co-use with alcohol and tobacco among young adults has continued to rise in recent years. Considerable research has shown that co-use places individuals at greater risk for driving under the influence, poorer mental-health and cognition, and co-morbid substance use disorders when compared to single-substance use. Despite the increased prevalence and risk associated with the co-use of cannabis with other substances, the mechanisms underlying these associations remains unclear. It has been hypothesized that individuals engage in co-use to achieve greater subjective responses beyond that perceived with the use of each substance alone. Given prior research has found inconsistent and null findings for outcomes related to patterns of co-use, this suggests changes may be complex and require more careful examination of within- person processes. Previous studies have also shown that subjective responses to cannabis may underlie or coincide the development of cannabis use disorder (CUD); however, it is unclear from the existing literature whether subjective drug effects of cannabis resulting from co-use with other substances, such as alcohol and tobacco, increases the risk for hazardous use over time. The proposed study will utilize advanced statistical methodology (e.g., multilevel modeling, longitudinal analyses) to examine ecological momentary assessment and longitudinal data in young adult recreational cannabis users from a NIDA R01 project. Aim 1 of the proposal will examine how cannabis co-use occasions with alcohol or tobacco (drug, ordering, timing) affects subjective drug abuse liability effects of cannabis; and Aim 2 will examine whether these subjective responses to co-use predict hazardous cannabis use one year later. Identifying underlying mechanisms of risk associated with cannabis co-use will help to develop better tailored intervention approaches to decrease the public health burden of CUDs among young adults.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2023 ( Subtotal = $46,206 )
2023	2023	PENNSYLVANIA STATE UNIVERSITY, THE	201 OLD MAIN	UNIVERSITY PARK	PA	16802	CENTRE	USA	Drug Abuse and Addiction Research Programs	000	2	6/8/2023	NON-COMPETING CONTINUATION	$46,206
														Subtotal = $46,206

Issue Date FY: 2022 ( Subtotal = $45,264 )
2022	2022	PENNSYLVANIA STATE UNIVERSITY, THE	201 OLD MAIN	UNIVERSITY PARK	PA	16802	CENTRE	USA	Drug Abuse and Addiction Research Programs	002	1	5/23/2022	NEW	-$1
2022	2022	PENNSYLVANIA STATE UNIVERSITY, THE	201 OLD MAIN	UNIVERSITY PARK	PA	16802	CENTRE	USA	Drug Abuse and Addiction Research Programs	001	1	4/20/2022	NEW	$717
2022	2022	PENNSYLVANIA STATE UNIVERSITY, THE	201 OLD MAIN	UNIVERSITY PARK	PA	16802	CENTRE	USA	Drug Abuse and Addiction Research Programs	000	1	3/3/2022	NEW	$44,548
2022	2022	PENNSYLVANIA STATE UNIVERSITY, THE	201 OLD MAIN	UNIVERSITY PARK	PA	16802	CENTRE	USA	Drug Abuse and Addiction Research Programs	003	1	5/23/2022	NEW	$0
														Subtotal = $45,264

Grand Total All Awards = $91,470

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Effects of Alcohol and Tobacco Co-use on Momentary Subjective Cannabis Effects: Risks for Increasingly Hazardous Cannabis Use

Award Number: F31DA056066

ORGANIZATION: NATIONAL INSTITUTE ON DRUG ABUSE

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: FELLOWSHIP/SCHOLARSHIP/STUDENT LOANS

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