Real-world community-based settings are not equipped to deploy and sustain resource-intensive evidence-based interventions (EBIs) for people with physical/mobility disabilities. The goal of this DRRP is to examine the feasibility, efficacy and effectiveness of an innovative EBI (Movement-2-Music, M2M©) that has been successfully developed and tested in two disability groups (multiple sclerosis and stroke) and will be examined in this application for a broader range of people with physical/mobility disabilities. The DRRP contains three sequenced projects that address the FOA research stage requirements of intervention efficacy and scale-up. Study 1 (intervention efficacy) is a randomized controlled efficacy trial examining the effects of a 12-week M2M© intervention in 108 adults with physical/mobility disabilities organized by three functional levels: Level I – sitting exercise only; Level II – sitting and standing exercise (with/without support while standing); and Level III sitting/standing exercise with emphasis on right/left side (for participants with hemiparesis). Study 2 involves a 12-week randomized pilot implementation trial testing the delivery methods of the M2M© intervention on 54 study participants in two different settings: a community-based YMCA and home-based telehealth (i.e., teleexercise) platform. Study 3 is a type 1 hybrid effectiveness-implementation RCT that will compare the effectiveness of two delivery methods of M2M©. Two hundred and forty participants will be randomized to the YMCA community-based version of M2M© (Y-M2M©, n=120) or a Blended YMCA/home-based teleexercise version (B-M2M©, n=120). Primary outcomes include improved physical and psychosocial health. Training includes the development of a certificate in disability content and M2M© with the American College of Sports Medicine (ACSM). Dissemination of findings will include M2M© content distributed nationally through the National Center on Health, Physical Acti
vity and Disability (NCHPAD).