HHS Recovery Act Recipient Reporting Readiness Tool

Step 4. Review and Copy the Grant Awards Data

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Prime Recipient Report

Award Detail for: INFLUENCE OF SURFACE ADHESION FORCES ON VOCAL FOLD STRESS AND FUNCTION
Recipient Name:BRIGHAM YOUNG UNIVERSITY
DUNS Number: 009094012
D-177 ASB
PROVO, UT 84602

Reporting Information

Award Type*: Grant

Award Number*: 3R03DC008200-03S1

Final Report*: Recipient responsible for this data

Award Recipient Information

Recipient DUNS Number*: 009094012

Recipient Account Number: Recipient responsible for this data

Recipient Congressional District*: 3

Award Information

Funding Agency Code*: 7529

Awarding Agency Code*:7529

Award Date*: 07-15-2009

Amount of Award*: $ 42,000

Program Source (TAS)*: 750905

CFDA Number*: 93.701

Sub Account Number for Program Source (TAS)*: Recipient responsible for this data

Total Number of Sub Awards to Individuals*: Recipient responsible for this data

Total Amount of Sub Awards to Individuals*: Recipient responsible for this data

Total Number of Payments to Vendors less than $25,000/award*: Recipient responsible for this data

Total Amount of Payments to Vendors less than $25,000/award*: Recipient responsible for this data

Total Number of Sub Awards less than $25,000/award*: Recipient responsible for this data

Total Amount of Sub Awards less than $25,000/award*: Recipient responsible for this data

Award Description* DESCRIPTION (provided by applicant): Stress within vocal fold tissue is a primary source of vocal fold discomfort and damage. Identifying the influence of various factors that contribute to vocal fold stress can lead to improved clinical care, improved medical procedures, and increased awareness of individuals in the workforce who rely on voice use. One source of vocal fold stress is that which results from increased adhesive properties of the glottal airway surface liquid (ASL). Such situations can arise, for example, from dehydration. The goal of the proposed research is to develop models for studying the glottal ASL and use these models to explore the sensitivity of vocal fold stress and function to ASL adhesion forces. Pursuit of this goal is planned through the use of complementary analytical, synthetic, and computational vocal fold models according to the following research aims: Specific Aim 1: Develop airway surface liquid models for use in computational vocal fold models. Develop analytical and computational (finite element) models of glottal airway surface liquid (ASL). Incorporate two- layer ASL representation, namely, Newtonian sol layer and non-Newtonian mucus layer. Validate models with experiments carried out using mono- and bi-layer Newtonian and non-Newtonian fluids, including sol and mucus simulants. Specific Aim 2: Incorporate airway surface liquid models in self-oscillating computational vocal fold models. Incorporate ASL models into self-oscillating models of vocal fold vibration, including a two-dimensional, body- cover finite element (FE) vocal fold model and a three-dimensional, multi-tissue-layer FE vocal fold model. Validate models with data from experiments using synthetic self-oscillating vocal fold models. Specific Aim 3: Investigate sensitivity of vocal fold stress and function during phonation to airway surface liquid properties using computational vocal fold models. Using the FE vocal fold + ASL models (Specific Aim 2), identify conditions in which ASL adhesion forces become sufficiently large so as to significantly influence vocal fold stress and function. Perform parametric sensitivity studies using different values of ASL thickness and properties, vocal fold tissue layer geometry and properties, and oscillation parameters. Observables include stress within the vocal fold cover, oscillation frequency and amplitude, open quotient, glottal airflow waveforms, and frequency vs. pressure and flow rate vs. pressure relationships. Accomplishing the above aims will impact several areas of voice care and research, including: engineered tissue development for replacing damaged vocal fold tissue, vocal fold prosthesis and implant design, voice disorder treatment, and voice production research. Project Narrative: The airway surface liquid (ASL) lines the human respiratory airways. Under certain conditions the glottal ASL is subject to dehydration and other property changes that may adversely influence voice production. The objective of the proposed research is to develop models of the glottal ASL and explore its influence on vocal fold tissue stress and vibratory behavior.

Project Information

Project Name or Project/Program Title*: INFLUENCE OF SURFACE ADHESION FORCES ON VOCAL FOLD STRESS AND FUNCTION

Project Status*: Recipient responsible for this data

Total Federal Amount of ARRA Funds Received/Invoiced*: Recipient responsible for this data

Number of Jobs*: Recipient responsible for this data

Description of Jobs Created*: Recipient responsible for this data

Quarterly Activities/Project Description*: Recipient responsible for this data

Activity Code (NAICS or NTEE-NPC)*: Recipient responsible for this data

Total Federal Amount of ARRA Expenditure* (Enter the cumulative total amount of Recovery Funds received that were expended to projects or activities. Refer to the Data Model for details on how to calculate this amount.): Recipient responsible for this data

Total Federal ARRA Infrastructure Expenditure Recipient responsible for this data

Infrastructure Contact Name: Recipient responsible for this data

Infrastructure Contact Email: Recipient responsible for this data

Infrastructure Contact Phone: Recipient responsible for this data

Infrastructure Contact Phone Ext: Recipient responsible for this data

Infrastructure Contact Street Address 1: D-177 ASB

Infrastructure Contact Street Address 2: Not Available

Infrastructure Contact Street Address 3: Recipient responsible for this data

Infrastructure City: PROVO

Infrastructure State: UT

Infrastructure ZIP Code+4: 84602

Infrastructure Purpose and Rationale (If applicable, enter an explanation about how the infrastructure investment will contribute to one or more purposes of the Recovery Act. Refer to the Data Model for details on what to report. 4000 characters or less.): Recipient responsible for this data

Primary Place of Performance

Street Address 1: OFFICE OF RESEARCH & CREATIVE ACTIVITIES A-285 ASB

Street Address 2: PROVO

City*: PROVO

State*: UT

ZIP Code+4*: 846021231

Congressional District*: 3

Country*: US

Recipient Highly Compensated Officers

Prime Recipient Indication of Reporting Applicability*: Recipient responsible for this data

1. Officer Name and Compensation: Recipient responsible for this data
2. Officer Name and Compensation: Recipient responsible for this data
3. Officer Name and Compensation: Recipient responsible for this data
4. Officer Name and Compensation: Recipient responsible for this data
5. Officer Name and Compensation: Recipient responsible for this data

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