HHS Recovery Act Recipient Reporting Readiness Tool
Step 4. Review and Copy the Grant Awards Data
TAGGS provides some – but not all – of the data needed for the Recipient Report. Recipients are responsible for directly collecting and reporting all required data to FederalReporting.gov. Data that HHS does not currently collect are highlighted in yellow. Do not copy this highlighted information. Please enter the appropriate data for your organization in these required fields. For assistance with entering these data please contact FederalReporting.gov.
You may capture the data HHS does provide by copying data from this screen and pasting it into the reporting format of your choice, such as the Excel spreadsheet template, the XML template, or by logging into the online form. For assistance with copying and pasting these data please email our help desk at Readiness Help
Prime Recipient Report
Award Detail for: ROLE OF CILIA IN MAMMALIAN TOOTH PATTERNINGRecipient Name:MEDICAL UNIVERSITY OF SOUTH CAROLINA
DUNS Number: 183710748
19 HAGOOD AVE, SUITE 608
CHARLESTON, SC 29403-5120
Reporting Information
Award Type*: Grant
Award Number*: 1R03DE019506-01A1
Final Report*: Recipient responsible for this data
Award Recipient Information
Recipient DUNS Number*: 183710748
Recipient Account Number: Recipient responsible for this data
Recipient Congressional District*: 1
Award Information
Funding Agency Code*: 7529
Awarding Agency Code*:7529
Award Date*: 09-16-2009
Amount of Award*: $ 110,625
Program Source (TAS)*: 750874
CFDA Number*: 93.701
Sub Account Number for Program Source (TAS)*: Recipient responsible for this data
Total Number of Sub Awards to Individuals*: Recipient responsible for this data
Total Amount of Sub Awards to Individuals*: Recipient responsible for this data
Total Number of Payments to Vendors less than $25,000/award*: Recipient responsible for this data
Total Amount of Payments to Vendors less than $25,000/award*: Recipient responsible for this data
Total Number of Sub Awards less than $25,000/award*: Recipient responsible for this data
Total Amount of Sub Awards less than $25,000/award*: Recipient responsible for this data
Award Description* DESCRIPTION (provided by applicant): Cilia are microtubule-based organelles that have long been observed on most mammalian cells. While their presence has been known, their diverse functions in mammalian development and signaling are poorly understood. Cilia have recently been shown to be essential for hedgehog signaling, PDGFRAA signaling and in modulating Wnt responses. Tooth development in mice is initiated during embryogenesis and requires complex signaling between the oral ectoderm and underlying mesenchyme. As development progresses, ectodermal cells contribute to the superficial structures of the tooth including the enamel while the mesenchyme differentiates into many cell types including the dental pulp cells and odontoblasts which secrete dentin below the enamel. Cilia have been identified on the odontoblasts and mice with partial loss of cilia function have defects in the patterning of the teeth suggesting a role for cilia during the patterning and development of the murine dentition. The goal of this application is to investigate cilia function in tooth formation using a conditional allele of the cilia gene Tg737 and an inducible Cre recombinase to disrupt cilia at two distinct stages of tooth development. The role of cilia during tooth initiation and morphogenesis will be investigated by examining the patterning and development of teeth. After cilia disruption, the resulting teeth will be examined using histology and in situ hybridization. Overall the data obtained will provide preliminary to support more detailed studies. PUBLIC HEALTH RELEVANCE: A growing number of pleiotropic syndromes have been associated with mutations in proteins localized to the cilium and/or basal body and defects in tooth number or structure are evident in patients. In order to better understand how cilia/basal body defects lead to alterations in the dentition, additional work is necessary.
Project Information
Project Name or Project/Program Title*: ROLE OF CILIA IN MAMMALIAN TOOTH PATTERNING
Project Status*: Recipient responsible for this data
Total Federal Amount of ARRA Funds Received/Invoiced*: Recipient responsible for this data
Number of Jobs*: Recipient responsible for this data
Description of Jobs Created*: Recipient responsible for this data
Quarterly Activities/Project Description*: Recipient responsible for this data
Activity Code (NAICS or NTEE-NPC)*: Recipient responsible for this data
Total Federal Amount of ARRA Expenditure* (Enter the cumulative total amount of Recovery Funds received that were expended to projects or activities. Refer to the Data Model for details on how to calculate this amount.): Recipient responsible for this data
Total Federal ARRA Infrastructure Expenditure Recipient responsible for this data
Infrastructure Contact Name: Recipient responsible for this data
Infrastructure Contact Email: Recipient responsible for this data
Infrastructure Contact Phone: Recipient responsible for this data
Infrastructure Contact Phone Ext: Recipient responsible for this data
Infrastructure Contact Street Address 1: 19 HAGOOD AVE, SUITE 608
Infrastructure Contact Street Address 2: Not Available
Infrastructure Contact Street Address 3: Recipient responsible for this data
Infrastructure City: CHARLESTON
Infrastructure State: SC
Infrastructure ZIP Code+4: 29403-5120
Infrastructure Purpose and Rationale (If applicable, enter an explanation about how the infrastructure investment will contribute to one or more purposes of the Recovery Act. Refer to the Data Model for details on what to report. 4000 characters or less.): Recipient responsible for this data
Primary Place of Performance
Street Address 1: 19 HAGOOD AVE., SUITE 606MSC 808
Street Address 2: CHARLESTON
City*: CHARLESTON
State*: SC
ZIP Code+4*: 29425
Congressional District*: 1
Country*: US
Recipient Highly Compensated Officers
Prime Recipient Indication of Reporting Applicability*: Recipient responsible for this data
- Officer Name and Compensation: Recipient responsible for this data
- Officer Name and Compensation: Recipient responsible for this data
- Officer Name and Compensation: Recipient responsible for this data
- Officer Name and Compensation: Recipient responsible for this data
- Officer Name and Compensation: Recipient responsible for this data
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Use in the Recipient Report
The information provided by this tool is baseline data that the Recipient should include in the Recipient Report that must be submitted to FederalReporting.gov beginning October 1, 2009. The data from this tool can be cut and pasted directly into the Recipient Report.
