HHS Recovery Act Recipient Reporting Readiness Tool
Step 4. Review and Copy the Grant Awards Data
TAGGS provides some – but not all – of the data needed for the Recipient Report. Recipients are responsible for directly collecting and reporting all required data to FederalReporting.gov. Data that HHS does not currently collect are highlighted in yellow. Do not copy this highlighted information. Please enter the appropriate data for your organization in these required fields. For assistance with entering these data please contact FederalReporting.gov.
You may capture the data HHS does provide by copying data from this screen and pasting it into the reporting format of your choice, such as the Excel spreadsheet template, the XML template, or by logging into the online form. For assistance with copying and pasting these data please e-mail our help desk at Readiness Help.
| Recipient Report: Grant or Loan | ||
| Prime Recipient |
| Reporting Information | ||
| Award Type | Award Number | Final Report |
| Grant | 5RC2HL101625-02 | Recipient responsible for this data |
| Award Recipient Information | ||
| Recipient DUNS Number | Recipient Account Number | Recipient Congressional District |
| 071508873 | Recipient responsible for this data | 5 |
| Award Information | ||
| Funding Agency Code | Awarding Agency Code | Award Date |
| 7529 | 7529 | 08-25-2010 |
| Amount of Award | Sub Account Number for Program Source (TAS) | |
| $ 621,710 | Recipient responsible for this data | |
| Program Source (TAS)* | CFDA Number | |
| 750871 | 93.701 | |
| Total Number of Sub Awards to Individuals | Total Amount of Sub Awards to Individuals | |
| Recipient responsible for this data | Recipient responsible for this data | |
| Total Number of Payments to Vendors less than $25,000/award | Total Amount of Payments to Vendors less than $25,000/award | |
| Recipient responsible for this data | Recipient responsible for this data | |
| Total Number of Sub Awards less than $25,000/award | Total Amount of Sub Awards less than $25,000/award | |
| Recipient responsible for this data | Recipient responsible for this data | |
| Award Description | ||
| DESCRIPTION (provided by applicant): The aim of this two-year "Grand Opportunities" ("GO") proposal is to construct a detailed and comprehensive profile of the molecular biology of cardiac function in a hibernating mammal. In compliance with "GO" program requirements the proposed project is a convergence of expertise at the University of Minnesota involving multiple campuses and facilities including the Biomedical Genomics Center and Minnesota Supercomputing Institute in the Twin Cities, the School of Medicine, Department of Biology and the Department of Mathematics & Statistics in Duluth, and an industrial partner, Tethys Bioscience. Hibernation is a natural adaptation that allows certain mammals to survive physiological extremes that result in death in humans. The fundamental adaptation present in natural hibernators is greatly reduced body temperature, metabolism and respiration- conditions that buy precious time in cases of myocardial ischemia, traumatic injury and cardiac arrest. Our central hypothesis is that changes in hibernation-specific gene expression and lipid composition provide protection against myocardial damage normally associated with ischemia and reperfusion injury. High-throughput instrumentation and advances in computational power have placed us in a unique position to identify genes that control the hibernation phenotype and to link their expression to cardiac function under extreme conditions. We will identify genes that are expressed in active and hibernating thirteen-lined ground squirrels (Spermophilus tridecemlineatus) by high-throughput cDNA sequencing using the Roche 454 system. This massive sequencing platform will generate statistically high numbers of cDNA sequences that will be processed by the Minnesota Supercomputing Institute to determine patterns of gene expression throughout the hibernation season. Due to the importance of lipids as fuel, and as structural and signaling molecules, we will enlist the services of a corporate partner, Tethys Bioscience (www.lipomics.com), to perform a comprehensive survey of heart, white adipose tissue and serum lipids. Tethys specializes in quantifying over 450 lipid metabolites in plasma/sera and tissue. At the conclusion of this two-year project we will have a detailed molecular profile of cardiac function in mammalian hibernators and a better understanding of how this natural adaptation results in the avoidance of the pathological consequences of hypothermia, ischemia and reperfusion injury. PUBLIC HEALTH RELEVANCE: The aim of the research described in this proposal is to construct a detailed and comprehensive profile of the molecular biology of cardiac function in hibernating mammals. The fundamental adaptation present in natural hibernators is greatly reduced body temperature, metabolism and respiration-conditions that buy precious time in cases of myocardial ischemia, traumatic injury and cardiac arrest. Our central hypothesis is that hibernation-specific changes in gene expression and the composition of lipids provides protection against myocardial damage normally associated with ischemia and reperfusion injury. | ||
| Project Information | ||||||||||||||||||||||||||
| Project Name or Project/Program Title |
Project Status | Total Federal Amount ARRA Funds Received/Invoiced |
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| GENETIC CONTROL OF HEART FUNCTION IN A HIBERNATING MAMMAL | Recipient responsible for this data | Recipient responsible for this data | ||||||||||||||||||||||||
| Number of Jobs | Description of Jobs Created | |||||||||||||||||||||||||
| Recipient responsible for this data | Recipient responsible for this data | |||||||||||||||||||||||||
| Quarterly Activities/Project Description | ||||||||||||||||||||||||||
| Recipient responsible for this data | ||||||||||||||||||||||||||
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| Total Federal Amount of ARRA Expenditure |
Total Federal ARRA Infrastructure Expenditure |
Infrastructure Contact Name | ||||||||||||||||||||||||
| Recipient responsible for this data | Recipient responsible for this data | Recipient responsible for this data | ||||||||||||||||||||||||
| Infrastructure Contact Email | Infrastructure Contact Phone | Infrastructure Contact Phone Ext. | ||||||||||||||||||||||||
| Recipient responsible for this data | Recipient responsible for this data | Recipient responsible for this data | ||||||||||||||||||||||||
| Infrastructure Contact Street Address 1 | Infrastructure Contact Street Address 2 | Infrastructure Contact Street Address 3 | ||||||||||||||||||||||||
| 106 PLEASANT SE, 210 FRASER HL | Not Available | Recipient responsible for this data | ||||||||||||||||||||||||
| Infrastructure City | Infrastructure State | Infrastructure ZIP Code+4 | ||||||||||||||||||||||||
| MINNEAPOLIS | MN | 55455 | ||||||||||||||||||||||||
| Infrastructure Purpose and Rationale | ||||||||||||||||||||||||||
| Recipient responsible for this data | ||||||||||||||||||||||||||
| Primary Place of Performance | ||
| Street Address 1 | Street Address 2 | City |
| Not Available | Recipient responsible for this data | DULUTH |
| State | Zip Code+4 | Congressional District |
| MN | 55812 | Not Available |
| Country | ||
| US | ||
| Recipient Highly Compensated Officers | |||
| Prime Recipient Indication of Reporting Applicability | # | Officer Name | Officer Compensation |
| Recipient responsible for this data | 1 | Recipient responsible for this data | Recipient responsible for this data |
| 2 | Recipient responsible for this data | Recipient responsible for this data | |
| 3 | Recipient responsible for this data | Recipient responsible for this data | |
| 4 | Recipient responsible for this data | Recipient responsible for this data | |
| 5 | Recipient responsible for this data | Recipient responsible for this data | |
This concludes the current search.
To begin a new search, return to the HHS Recovery Act Recipient Reporting Readiness Tool.
USE IN THE RECIPIENT REPORT
The information provided by this tool is baseline data that the Recipient should include in the Recipient Report that must be submitted to FederalReporting.gov beginning October 1, 2009. The data from this tool can be cut and pasted directly into the Recipient Report.
