HHS Recovery Act Recipient Reporting Readiness Tool
Step 4. Review and Copy the Grant Awards Data
TAGGS provides some – but not all – of the data needed for the Recipient Report. Recipients are responsible for directly collecting and reporting all required data to FederalReporting.gov. Data that HHS does not currently collect are highlighted in yellow. Do not copy this highlighted information. Please enter the appropriate data for your organization in these required fields. For assistance with entering these data please contact FederalReporting.gov.
You may capture the data HHS does provide by copying data from this screen and pasting it into the reporting format of your choice, such as the Excel spreadsheet template, the XML template, or by logging into the online form. For assistance with copying and pasting these data please e-mail our help desk at Readiness Help.
| Recipient Report: Grant or Loan | ||
| Prime Recipient |
| Reporting Information | ||
| Award Type | Award Number | Final Report |
| Grant | 5RC1AI086061-02 | Recipient responsible for this data |
| Award Recipient Information | ||
| Recipient DUNS Number | Recipient Account Number | Recipient Congressional District |
| 078861598 | Recipient responsible for this data | 15 |
| Award Information | ||
| Funding Agency Code | Awarding Agency Code | Award Date |
| 7529 | 7529 | 08-24-2010 |
| Amount of Award | Sub Account Number for Program Source (TAS) | |
| $ 500,000 | Recipient responsible for this data | |
| Program Source (TAS)* | CFDA Number | |
| 750845 | 93.701 | |
| Total Number of Sub Awards to Individuals | Total Amount of Sub Awards to Individuals | |
| Recipient responsible for this data | Recipient responsible for this data | |
| Total Number of Payments to Vendors less than $25,000/award | Total Amount of Payments to Vendors less than $25,000/award | |
| Recipient responsible for this data | Recipient responsible for this data | |
| Total Number of Sub Awards less than $25,000/award | Total Amount of Sub Awards less than $25,000/award | |
| Recipient responsible for this data | Recipient responsible for this data | |
| Award Description | ||
| DESCRIPTION (provided by applicant): This application addresses broad challenge area (15) Translational Science and specific Challenge Topic, 15-AI-106: translational research focused on high priority pathogens and basic research focused on resistance mechanisms. The research described herein can be initiated immediately and completed within two years. The work proposed will maintain or create three full time positions and will require the purchase of products and services from the biotech industry. In the longer term, the outcome of the proposed research may stimulate the economy by greatly reducing employee absenteeism due to influenza illness and eliciting the investment of vaccine companies in the optimization and manufacture of universal influenza vaccines. Specifically, we propose the development of novel influenza vaccine constructs which have the potential to protect against a wide range of antigenically-drifted variant viruses and against multiple subtypes influenza A viruses. The design of these constructs is based on our and others' recent observations that monoclonal antibodies which bind to the conserved stalk region of the influenza A virus hemagglutinin (HA) molecule are both broadly cross-reactive and neutralizing. The identified epitope is highly conformational, comprising portions of both the HA1 and HA2 subunits, and is located in the membrane proximal region of the HA protein. During natural infection or vaccination with conventional influenza vaccines, this region of the HA molecule is thought to be masked by the membrane distal portion of HA, a bulky and highly immunogenic globular head domain. Indeed, the immune response to vaccines currently in use is predominantly targeted against the globular head of HA; since this domain is very poorly conserved, current vaccines protect only against relatively small clusters of closely related strains. We have identified a way of expressing a modified HA molecule which lacks the globular head domain and maintains the structural integrity of the stalk region. This molecule forms the basis for a new generation of influenza vaccines which will induce broadly cross- neutralizing antibodies against the conserved stalk region. Such vaccines have the potential to provide protection against epidemic strains arising over several decades, obviating the need for annual influenza vaccination. In addition, vaccines based on the conserved HA stalk domain are predicted to be effective against influenza viruses of most (perhaps all) of the 16 HA subtypes and therefore to provide protection in the event of an influenza pandemic. PUBLIC HEALTH RELEVANCE: The research we propose is aimed at developing a new influenza virus vaccine which has the potential to protect against many distinct types of influenza virus. If successful, this vaccine could protect recipients against influenza for decades, rather than for just one or two years as the current vaccines do. In addition, since it would work against a broad range of influenza viruses, it would provide protection in the event of an influenza pandemic. | ||
| Project Information | ||||||||||||||||||||||||||
| Project Name or Project/Program Title |
Project Status | Total Federal Amount ARRA Funds Received/Invoiced |
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| DEVELOPMENT OF A UNIVERSAL INFLUENZA VIRUS VACCINE | Recipient responsible for this data | Recipient responsible for this data | ||||||||||||||||||||||||
| Number of Jobs | Description of Jobs Created | |||||||||||||||||||||||||
| Recipient responsible for this data | Recipient responsible for this data | |||||||||||||||||||||||||
| Quarterly Activities/Project Description | ||||||||||||||||||||||||||
| Recipient responsible for this data | ||||||||||||||||||||||||||
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| Total Federal Amount of ARRA Expenditure |
Total Federal ARRA Infrastructure Expenditure |
Infrastructure Contact Name | ||||||||||||||||||||||||
| Recipient responsible for this data | Recipient responsible for this data | Recipient responsible for this data | ||||||||||||||||||||||||
| Infrastructure Contact Email | Infrastructure Contact Phone | Infrastructure Contact Phone Ext. | ||||||||||||||||||||||||
| Recipient responsible for this data | Recipient responsible for this data | Recipient responsible for this data | ||||||||||||||||||||||||
| Infrastructure Contact Street Address 1 | Infrastructure Contact Street Address 2 | Infrastructure Contact Street Address 3 | ||||||||||||||||||||||||
| 1 GUSTAVE L LEVY PL, BOX 3500 | Not Available | Recipient responsible for this data | ||||||||||||||||||||||||
| Infrastructure City | Infrastructure State | Infrastructure ZIP Code+4 | ||||||||||||||||||||||||
| NEW YORK-NEW YORK | NY | 10029-6500 | ||||||||||||||||||||||||
| Infrastructure Purpose and Rationale | ||||||||||||||||||||||||||
| Recipient responsible for this data | ||||||||||||||||||||||||||
| Primary Place of Performance | ||
| Street Address 1 | Street Address 2 | City |
| BOX 1075 | Recipient responsible for this data | NEW YORK |
| State | Zip Code+4 | Congressional District |
| NY | 10029 | 14 |
| Country | ||
| US | ||
| Recipient Highly Compensated Officers | |||
| Prime Recipient Indication of Reporting Applicability | # | Officer Name | Officer Compensation |
| Recipient responsible for this data | 1 | Recipient responsible for this data | Recipient responsible for this data |
| 2 | Recipient responsible for this data | Recipient responsible for this data | |
| 3 | Recipient responsible for this data | Recipient responsible for this data | |
| 4 | Recipient responsible for this data | Recipient responsible for this data | |
| 5 | Recipient responsible for this data | Recipient responsible for this data | |
This concludes the current search.
To begin a new search, return to the HHS Recovery Act Recipient Reporting Readiness Tool.
USE IN THE RECIPIENT REPORT
The information provided by this tool is baseline data that the Recipient should include in the Recipient Report that must be submitted to FederalReporting.gov beginning October 1, 2009. The data from this tool can be cut and pasted directly into the Recipient Report.
