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HHS Recovery Act Recipient Reporting Readiness Tool

Step 4. Review and Copy the Grant Awards Data

TAGGS provides some – but not all – of the data needed for the Recipient Report. Recipients are responsible for directly collecting and reporting all required data to FederalReporting.gov. Data that HHS does not currently collect are highlighted in yellow. Do not copy this highlighted information. Please enter the appropriate data for your organization in these required fields. For assistance with entering these data please contact FederalReporting.gov.

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Award Detail for: MODULAR SURFACE PLASMON RESONANCE BIOSENSOR FOR IN-VITRO DETERMINATION OF PROTEIN
UNIVERSITY OF DELAWARE
DUNS Number: 059007500
210 HULLIHEN HALL
NEWARK, DE 19716
Recipient Report: Grant or Loan
Prime Recipient

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Reporting Information
Award Type Award Number Final Report
Grant 5R01EB004761-07 Recipient responsible for this data

Award Recipient Information
Recipient DUNS Number Recipient Account Number Recipient Congressional District
059007500 Recipient responsible for this data Not Available

Award Information
Funding Agency Code Awarding Agency Code Award Date
7529 7529 04-15-2010
Amount of Award Sub Account Number for Program Source (TAS)  
$ 370,409 Recipient responsible for this data
Program Source (TAS)* CFDA Number 
750899 93.701
Total Number of Sub Awards to Individuals Total Amount of Sub Awards to Individuals
Recipient responsible for this data Recipient responsible for this data
Total Number of Payments to Vendors less than $25,000/award Total Amount of Payments to Vendors less than $25,000/award
Recipient responsible for this data Recipient responsible for this data
Total Number of Sub Awards less than $25,000/award Total Amount of Sub Awards less than $25,000/award
Recipient responsible for this data Recipient responsible for this data
Award Description
This project combines electrokinetic (EK) methods with surface plasmon resonance (SPR) spectroscopy to construct a flexible, modular lab-on-a-chip platform for determination of target biomarkers. Small volume channels are etched into a dielectric substrate where EK methods for concentration and separation (i.e. dielectrophoresis and electrophoretic capture) of target analytes from the other compounds in the biofluids are employed to condition the sample for SPR detection. For example dielectrophoresis and electrophoretic capture will be employed to locally concentrate the target analytes in the microfluidic channel while minimizing the local concentration of interfering proteins. Gold sensing pads can be employed for direct label-free SPR analyses, coated with bioreceptors to increase sensitivity and selectivity, or coated with bioreceptors for the analysis followed by signal amplification with the another antibody to the target biomarker. Methods for signal enhancement such as antibody sandwich assays will be included with the lab-on-a-chip design to achieve a greater degree of sensitivity. This sensor will be applied to detection of biomarkers for myocardial infarction. The proposed platform offers the following attributes beneficial to any bioassay: " The modular, 'chip' based sensing platform can separate, concentrate, and quantify multiple protein and peptide biomarkers required for a panel assay. " Electrokinetic methods and SPR detection with sandwich assays are both appropriate for analyzing physiological levels of proteins and peptides. " The system is ideally suited for small volume analyses. EP and DEP work best in small channels approximately 10 to 100 microns in diameter. SPR is sensitive to refractive index changes within 200 nm of the gold sensing pads. " EK can rapidly separate and concentrate analytes from complex mixtures based on electrophoretic mobility. High resolution separations are possible and 1000-fold preconcentration can be achieved with dielectrophoresis or addressable electrophoretic capture.

Project Information
Project Name or
Project/Program Title
Project Status Total Federal Amount ARRA Funds
Received/Invoiced
MODULAR SURFACE PLASMON RESONANCE BIOSENSOR FOR IN-VITRO DETERMINATION OF PROTEIN Recipient responsible for this data Recipient responsible for this data
Number of Jobs Description of Jobs Created
Recipient responsible for this data Recipient responsible for this data
Quarterly Activities/Project Description
Recipient responsible for this data
 
Activity Code (NAICS or NTEE-NPC)
1Recipient responsible for this data2Recipient responsible for this data
3Recipient responsible for this data4Recipient responsible for this data
5Recipient responsible for this data6Recipient responsible for this data
7Recipient responsible for this data8Recipient responsible for this data
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Total Federal Amount of ARRA
Expenditure
Total Federal ARRA
Infrastructure Expenditure
Infrastructure Contact Name
Recipient responsible for this data Recipient responsible for this data Recipient responsible for this data
Infrastructure Contact Email Infrastructure Contact Phone Infrastructure Contact Phone Ext.
Recipient responsible for this data Recipient responsible for this data Recipient responsible for this data
Infrastructure Contact Street Address 1 Infrastructure Contact Street Address 2 Infrastructure Contact Street Address 3
210 HULLIHEN HALL Not Available Recipient responsible for this data
Infrastructure City Infrastructure State Infrastructure ZIP Code+4
NEWARK DE 19716
Infrastructure Purpose and Rationale
Recipient responsible for this data

Primary Place of Performance
Street Address 1 Street Address 2 City
BROWN LAB Recipient responsible for this data NEWARK
State Zip Code+4 Congressional District
DE 19716 1
Country  
US

Recipient Highly Compensated Officers
Prime Recipient Indication of Reporting Applicability # Officer Name Officer Compensation
Recipient responsible for this data 1 Recipient responsible for this data Recipient responsible for this data
2 Recipient responsible for this data Recipient responsible for this data
3 Recipient responsible for this data Recipient responsible for this data
4 Recipient responsible for this data Recipient responsible for this data
5 Recipient responsible for this data Recipient responsible for this data

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