HHS Recovery Act Recipient Reporting Readiness Tool
Step 4. Review and Copy the Grant Awards Data
TAGGS provides some – but not all – of the data needed for the Recipient Report. Recipients are responsible for directly collecting and reporting all required data to FederalReporting.gov. Data that HHS does not currently collect are highlighted in yellow. Do not copy this highlighted information. Please enter the appropriate data for your organization in these required fields. For assistance with entering these data please contact FederalReporting.gov.
You may capture the data HHS does provide by copying data from this screen and pasting it into the reporting format of your choice, such as the Excel spreadsheet template, the XML template, or by logging into the online form. For assistance with copying and pasting these data please e-mail our help desk at Readiness Help.
| Recipient Report: Grant or Loan | ||
| Prime Recipient |
| Reporting Information | ||
| Award Type | Award Number | Final Report |
| Grant | 2R01AA009838-14 | Recipient responsible for this data |
| Award Recipient Information | ||
| Recipient DUNS Number | Recipient Account Number | Recipient Congressional District |
| 041544081 | Recipient responsible for this data | 15 |
| Award Information | ||
| Funding Agency Code | Awarding Agency Code | Award Date |
| 7529 | 7529 | 06-23-2009 |
| Amount of Award | Sub Account Number for Program Source (TAS) | |
| $ 387,718 | Recipient responsible for this data | |
| Program Source (TAS)* | CFDA Number | |
| 750909 | 93.701 | |
| Total Number of Sub Awards to Individuals | Total Amount of Sub Awards to Individuals | |
| Recipient responsible for this data | Recipient responsible for this data | |
| Total Number of Payments to Vendors less than $25,000/award | Total Amount of Payments to Vendors less than $25,000/award | |
| Recipient responsible for this data | Recipient responsible for this data | |
| Total Number of Sub Awards less than $25,000/award | Total Amount of Sub Awards less than $25,000/award | |
| Recipient responsible for this data | Recipient responsible for this data | |
| Award Description | ||
| DESCRIPTION (provided by applicant): This project explores continuing post-developmental neurogenesis and non-neuronal cytogenesis as processes that could be harnessed to aid in rehabilitation of the fetal alcohol-damaged brain. We have found that the capacity for post-weaning cytogenesis in adolescence and young adulthood is present, even enhanced, in the motor cortex of rats given binge-like alcohol exposure during the neonatal period of rapid brain growth, compared to unexposed controls. However, the alcohol-exposed rats fall behind their controls in preserving these newly-generated cells as they grow older. In the dentate gyrus of the hippocampus, a region known to generate new neurons post-developmentally and into adulthood, the number of adult-generated cells was similar in alcohol-exposed and control rats, but the alcohol-exposed rats again failed to preserve these new cells in the long term, falling behind their unexposed control counterparts. Overall, early alcohol exposure did not prevent genesis of new cells, but affected neurogenesis in dentate gyrus, and fewer of these cells survived. In contrast, increased voluntary physical exercise in adolescent rats (under social housing conditions) in a running wheel did increase cytogenesis and neurogenesis both in alcohol-exposed and control animals, but these new cells persisted less well in the alcohol-exposed rats than in controls. The goal of the proposed work is to determine whether and, if so, how combinations of experience, including physical exercise and learning in a physically stimulating toy-equipped environment, can be used to drive cell genesis and promote survival of newly-generated cells in a manner that positively influences brain function. The effects of these manipulations will be assessed both histologically in terms of the relative numbers of neurons and non- neuronal cells, and functionally in terms of performance on a set of behavioral tasks that depend on functional or structural plasticity in the hippocampus. Histological measures will use homologs to BrdU that are independently immuno-detectable, allowing populations of cells generated at different times to be independently assessed. Behavioral tests appropriate to the assessment of hippocampal function will be assessed in independent sets of animals, including trace eyeblink conditioning, trace fear conditioning (both contextual and CS-elicited fear), and spatial working memory in a water maze task. By combining age-specific markers of neurogenesis during the post-weaning intervention period with assessment of subsequent behavioral performance on hippocampal-dependent tasks, it will be possible to identify potential links between experience-dependent promotion of neurogenesis in the dentate gyrus and improved outcomes in cognitive behavior relevant to fetal alcohol spectrum disorders. PUBLIC HEALTH RELEVANCE Fetal alcohol spectrum disorders is a leading cause of developmental disability and mental retardation both in the US and in many other countries. Effective rehabilitative strategies directed at the damaged brain are at present not known. This project, using a rodent model of fetal alcohol damage, focuses on the capacity of some post-developmental brain regions to generate new neurons or other cell types and searches for ways to harness this capacity as a route to effective rehabilitative intervention. | ||
| Project Information | ||||||||||||||||||||||||||
| Project Name or Project/Program Title |
Project Status | Total Federal Amount ARRA Funds Received/Invoiced |
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| THERAPEUTIC MOTOR TRAINING AND FETAL ALCOHOL EFFECTS | Recipient responsible for this data | Recipient responsible for this data | ||||||||||||||||||||||||
| Number of Jobs | Description of Jobs Created | |||||||||||||||||||||||||
| Recipient responsible for this data | Recipient responsible for this data | |||||||||||||||||||||||||
| Quarterly Activities/Project Description | ||||||||||||||||||||||||||
| Recipient responsible for this data | ||||||||||||||||||||||||||
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| Total Federal Amount of ARRA Expenditure |
Total Federal ARRA Infrastructure Expenditure |
Infrastructure Contact Name | ||||||||||||||||||||||||
| Recipient responsible for this data | Recipient responsible for this data | Recipient responsible for this data | ||||||||||||||||||||||||
| Infrastructure Contact Email | Infrastructure Contact Phone | Infrastructure Contact Phone Ext. | ||||||||||||||||||||||||
| Recipient responsible for this data | Recipient responsible for this data | Recipient responsible for this data | ||||||||||||||||||||||||
| Infrastructure Contact Street Address 1 | Infrastructure Contact Street Address 2 | Infrastructure Contact Street Address 3 | ||||||||||||||||||||||||
| 109 COBLE HALL, 801 S WRIGHT S | Not Available | Recipient responsible for this data | ||||||||||||||||||||||||
| Infrastructure City | Infrastructure State | Infrastructure ZIP Code+4 | ||||||||||||||||||||||||
| CHAMPAIGN | IL | 61820 | ||||||||||||||||||||||||
| Infrastructure Purpose and Rationale | ||||||||||||||||||||||||||
| Recipient responsible for this data | ||||||||||||||||||||||||||
| Primary Place of Performance | ||
| Street Address 1 | Street Address 2 | City |
| OF SPONSORED PROGRAMS & RESEARCH ADMIN1901 S. FIRST STREET, SUITE A, MC-685 | Recipient responsible for this data | CHAMPAIGN |
| State | Zip Code+4 | Congressional District |
| IL | 61820 | 15 |
| Country | ||
| US | ||
| Recipient Highly Compensated Officers | |||
| Prime Recipient Indication of Reporting Applicability | # | Officer Name | Officer Compensation |
| Recipient responsible for this data | 1 | Recipient responsible for this data | Recipient responsible for this data |
| 2 | Recipient responsible for this data | Recipient responsible for this data | |
| 3 | Recipient responsible for this data | Recipient responsible for this data | |
| 4 | Recipient responsible for this data | Recipient responsible for this data | |
| 5 | Recipient responsible for this data | Recipient responsible for this data | |
This concludes the current search.
To begin a new search, return to the HHS Recovery Act Recipient Reporting Readiness Tool.
USE IN THE RECIPIENT REPORT
The information provided by this tool is baseline data that the Recipient should include in the Recipient Report that must be submitted to FederalReporting.gov beginning October 1, 2009. The data from this tool can be cut and pasted directly into the Recipient Report.
