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HHS Recovery Act Recipient Reporting Readiness Tool

Step 4. Review and Copy the Grant Awards Data

TAGGS provides some – but not all – of the data needed for the Recipient Report. Recipients are responsible for directly collecting and reporting all required data to FederalReporting.gov. Data that HHS does not currently collect are highlighted in yellow. Do not copy this highlighted information. Please enter the appropriate data for your organization in these required fields. For assistance with entering these data please contact FederalReporting.gov.

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Award Detail for: STATIC AND DYNAMIC LIGHT SCATTERING INSTRUMENTATION FOR MACROMOLECULAR CHARACTERI
CORNELL UNIVERSITY
DUNS Number: 872612445
373 PINE ROAD
ITHACA, NY 14850
Recipient Report: Grant or Loan
Prime Recipient

Reporting Information
Award Type Award Number Final Report
Grant 1S10RR027774-01 Recipient responsible for this data

Award Recipient Information
Recipient DUNS Number Recipient Account Number Recipient Congressional District
872612445 Recipient responsible for this data 22

Award Information
Funding Agency Code Awarding Agency Code Award Date
7529 7529 02-20-2010
Amount of Award Sub Account Number for Program Source (TAS)  
$ 171,005 Recipient responsible for this data
Program Source (TAS)* CFDA Number 
750847 93.701
Total Number of Sub Awards to Individuals Total Amount of Sub Awards to Individuals
Recipient responsible for this data Recipient responsible for this data
Total Number of Payments to Vendors less than $25,000/award Total Amount of Payments to Vendors less than $25,000/award
Recipient responsible for this data Recipient responsible for this data
Total Number of Sub Awards less than $25,000/award Total Amount of Sub Awards less than $25,000/award
Recipient responsible for this data Recipient responsible for this data
Award Description
DESCRIPTION (provided by applicant): This application requests funds for state-of-the-art Light Scattering (LS) devices for the characterization of macromolecular size, shape, oligomeric state and solution behavior. The instrumentation will consist of a Wyatt Technology Corporation DAWN HELEOS MALS (Multi-angle static light scattering) system, a WyattQELS (Quasi-Elastic-Light-Scattering, i.e., dynamic light scattering) instrument, and a Optilab rEX refractive index detector interfaced with an Agilent HPLC for in-line, real time LS analysis of samples separated by size exclusion and other forms of chromatography. This equipment will provide analytical capabilities currently not available at Cornell, essential for over a dozen active NIH supported grants. The proposed instrument will complement existing instrumentation at Cornell, particularly with respect to analyzing intact and exchanging protein complexes, protein-protein/ligand interactions and probing protein conformation. Accurate assessment of protein size and shape is a critical first step in molecular characterization. Moreover, associating systems underlie many mechanisms of signal transduction and biological regulation. It is becoming increasingly important to delineate conformational change from complex formation. Careful analyses of heterogenous samples by separation techniques combined with MALS/DLS can achieve these goals in a time and cost effective manner. Furthermore, many other forms of structural analysis such as x-ray crystallography and NMR spectroscopy rely on identifying conditions where samples are monodisperse and homogeneous. MALS/DLS analysis will greatly enhance and accelerate our ability to screen samples for crystallization trials and other biophysical experiments. The particular strengths of the proposed instrument are 1) Direct and absolute molecular weight measurements from simultaneous 18 angle static light scattering measurements; 2) Evaluation of the solution refractive index (n) and the change in refractive index with concentration (dn/dc) at the wavelength where static LS measurements are made; 3) Simultaneous assessment of diffusion coefficients from intensity fluctuations; 4) Sophisticated analysis software that provides standard deviations on each measurement; 5) Batch or flow cell analysis for examination of small samples or coupled HPLC eluates. The acquisition of this instrument will have an important impact on more than a dozen NIH-funded research projects, and will improve the research infrastructure of Cornell University and the education/training programs of students and researchers. It will accelerate and facilitate a wide range of research projects of Cornell faculty across three colleges relevant to life sciences research, and help to maintain Cornell's competitive position.

Project Information
Project Name or
Project/Program Title
Project Status Total Federal Amount ARRA Funds
Received/Invoiced
STATIC AND DYNAMIC LIGHT SCATTERING INSTRUMENTATION FOR MACROMOLECULAR CHARACTERI Recipient responsible for this data Recipient responsible for this data
Number of Jobs Description of Jobs Created
Recipient responsible for this data Recipient responsible for this data
Quarterly Activities/Project Description
Recipient responsible for this data
 
Activity Code (NAICS or NTEE-NPC)
1Recipient responsible for this data2Recipient responsible for this data
3Recipient responsible for this data4Recipient responsible for this data
5Recipient responsible for this data6Recipient responsible for this data
7Recipient responsible for this data8Recipient responsible for this data
9Recipient responsible for this data10Recipient responsible for this data
Total Federal Amount of ARRA
Expenditure
Total Federal ARRA
Infrastructure Expenditure
Infrastructure Contact Name
Recipient responsible for this data Recipient responsible for this data Recipient responsible for this data
Infrastructure Contact Email Infrastructure Contact Phone Infrastructure Contact Phone Ext.
Recipient responsible for this data Recipient responsible for this data Recipient responsible for this data
Infrastructure Contact Street Address 1 Infrastructure Contact Street Address 2 Infrastructure Contact Street Address 3
373 PINE ROAD Not Available Recipient responsible for this data
Infrastructure City Infrastructure State Infrastructure ZIP Code+4
ITHACA NY 14850
Infrastructure Purpose and Rationale
Recipient responsible for this data

Primary Place of Performance
Street Address 1 Street Address 2 City
TOWER ROADVETERINARY MEDICAL CENTER Recipient responsible for this data ITHACA
State Zip Code+4 Congressional District
NY 14853 Not Available
Country  
US

Recipient Highly Compensated Officers
Prime Recipient Indication of Reporting Applicability # Officer Name Officer Compensation
Recipient responsible for this data 1 Recipient responsible for this data Recipient responsible for this data
2 Recipient responsible for this data Recipient responsible for this data
3 Recipient responsible for this data Recipient responsible for this data
4 Recipient responsible for this data Recipient responsible for this data
5 Recipient responsible for this data Recipient responsible for this data

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USE IN THE RECIPIENT REPORT

The information provided by this tool is baseline data that the Recipient should include in the Recipient Report that must be submitted to FederalReporting.gov beginning October 1, 2009. The data from this tool can be cut and pasted directly into the Recipient Report.