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HHS Recovery Act Recipient Reporting Readiness Tool

Step 4. Review and Copy the Grant Awards Data

TAGGS provides some – but not all – of the data needed for the Recipient Report. Recipients are responsible for directly collecting and reporting all required data to FederalReporting.gov. Data that HHS does not currently collect are highlighted in yellow. Do not copy this highlighted information. Please enter the appropriate data for your organization in these required fields. For assistance with entering these data please contact FederalReporting.gov.

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Award Detail for: LOW-BURDEN TOOLS FOR IMPROVING PREDICTION AND DIAGNOSIS OF COGNITIVE IMPAIRMENT.
CORNELL UNIVERSITY
DUNS Number: 872612445
373 PINE ROAD
ITHACA, NY 14850
Recipient Report: Grant or Loan
Prime Recipient

Reporting Information
Award Type Award Number Final Report
Grant 1RC1AG036915-01 Recipient responsible for this data

Award Recipient Information
Recipient DUNS Number Recipient Account Number Recipient Congressional District
872612445 Recipient responsible for this data 22

Award Information
Funding Agency Code Awarding Agency Code Award Date
7529 7529 09-22-2009
Amount of Award Sub Account Number for Program Source (TAS)  
$ 377,787 Recipient responsible for this data
Program Source (TAS)* CFDA Number 
750845 93.701
Total Number of Sub Awards to Individuals Total Amount of Sub Awards to Individuals
Recipient responsible for this data Recipient responsible for this data
Total Number of Payments to Vendors less than $25,000/award Total Amount of Payments to Vendors less than $25,000/award
Recipient responsible for this data Recipient responsible for this data
Total Number of Sub Awards less than $25,000/award Total Amount of Sub Awards less than $25,000/award
Recipient responsible for this data Recipient responsible for this data
Award Description
DESCRIPTION (provided by applicant): This application addresses the broad Challenge Area: 15 Translational Science and the specific Challenge area Topic: 15-RR-101* Applied Translational Technology Development Memory declines, especially in recall, are hallmarks of healthy aging and conversion to cognitive impairment. Our goal is to use highly sensitive mathematical modeling techniques to improve the ability of clinical recall tests to predict future cognitive impairment and to diagnose current impairment. Our research will focus on one of the most widely used clinical tests of such declines, the Rey Auditory Verbal Learning Test (RAVLT). Our specific aims are to apply mathematical models to RAVLT data in order to: (a) substantially improve the ability of the RAVLT and similar clinical recall tests to predict future impairment and to diagnose current impairment; (b) separate different clinically important components of memory from one another in accordance with current theories of the memory processes that underlie performance on the RAVLT and similar tests; (c) identify the components of memory that differentiate cognitive changes that are associated with normal aging from changes that are associated with conversion to impairment; and (d) provide separate scores for different memory components of RAVLT data, which can be used to better predict behavioral and biological markers of future impairment and to identify current impairment. The research will consist of 2 phases, spanning 2 years. Both phases will rely on mathematical modeling tools and software that we have already developed. Our preliminary studies have shown that RAVLT-type tests are inherently noisy measures of impairment because 3 different memory processes are responsible for performance, but only 1 of them (gist-based reconstruction) is responsible for conversion to impairment. Therefore, in both phases of research, we will investigate how predictive and diagnostic power are improved when our modeling tools are used to remove this noise. Noise will be removed by computing separate scores for the reconstruction component of performance and for the other 2 components (direct access of verbatim traces and meta-cognitive confidence). During Phase I, this question will be investigated using a very large sample of subjects who participated in the Aging, Demographics, and Memory Study (ADAMS) portion of NIA's Healthy Retirement Study. The first phase will establish whether noise-free scores greatly improve our ability to separate groups of subjects that differ on biological markers of impairment (e.g., the ApoE genotype), behavioral markers of impairment (e.g., neuropsychological tests), and clinical diagnoses of impairment. During Phase II, this question will be investigated in a longitudinal study of 200 adults (aged 70 and above) who will be administered a neuropsychological test battery, and who will also be administered 3 versions of the RAVLT, spaced at 6-month intervals. The second phase will establish whether noise-free scores greatly improve our ability to differentiate individual people who differ in biological markers of impairment, behavioral markers of impairment, and clinical diagnoses of impairment. PUBLIC HEALTH RELEVANCE: This research will apply state-of-the-art mathematical models to clinical tests of memory to dramatically improve such tests' ability to predict future cognitive impairment in older adults and to diagnose current impairment. Findings will be used to develop low-burden tools that remove the noise for such tests and provide scores for the component memory process that are associated with conversion to impairment.

Project Information
Project Name or
Project/Program Title
Project Status Total Federal Amount ARRA Funds
Received/Invoiced
LOW-BURDEN TOOLS FOR IMPROVING PREDICTION AND DIAGNOSIS OF COGNITIVE IMPAIRMENT. Recipient responsible for this data Recipient responsible for this data
Number of Jobs Description of Jobs Created
Recipient responsible for this data Recipient responsible for this data
Quarterly Activities/Project Description
Recipient responsible for this data
 
Activity Code (NAICS or NTEE-NPC)
1Recipient responsible for this data2Recipient responsible for this data
3Recipient responsible for this data4Recipient responsible for this data
5Recipient responsible for this data6Recipient responsible for this data
7Recipient responsible for this data8Recipient responsible for this data
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Total Federal Amount of ARRA
Expenditure
Total Federal ARRA
Infrastructure Expenditure
Infrastructure Contact Name
Recipient responsible for this data Recipient responsible for this data Recipient responsible for this data
Infrastructure Contact Email Infrastructure Contact Phone Infrastructure Contact Phone Ext.
Recipient responsible for this data Recipient responsible for this data Recipient responsible for this data
Infrastructure Contact Street Address 1 Infrastructure Contact Street Address 2 Infrastructure Contact Street Address 3
373 PINE ROAD Not Available Recipient responsible for this data
Infrastructure City Infrastructure State Infrastructure ZIP Code+4
ITHACA NY 14850
Infrastructure Purpose and Rationale
Recipient responsible for this data

Primary Place of Performance
Street Address 1 Street Address 2 City
OFFICE OF SPONSORED PROGRAMS Recipient responsible for this data ITHACA
State Zip Code+4 Congressional District
NY 148502820 22
Country  
US

Recipient Highly Compensated Officers
Prime Recipient Indication of Reporting Applicability # Officer Name Officer Compensation
Recipient responsible for this data 1 Recipient responsible for this data Recipient responsible for this data
2 Recipient responsible for this data Recipient responsible for this data
3 Recipient responsible for this data Recipient responsible for this data
4 Recipient responsible for this data Recipient responsible for this data
5 Recipient responsible for this data Recipient responsible for this data

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The information provided by this tool is baseline data that the Recipient should include in the Recipient Report that must be submitted to FederalReporting.gov beginning October 1, 2009. The data from this tool can be cut and pasted directly into the Recipient Report.