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HHS Recovery Act Recipient Reporting Readiness Tool

Step 4. Review and Copy the Grant Awards Data

TAGGS provides some – but not all – of the data needed for the Recipient Report. Recipients are responsible for directly collecting and reporting all required data to FederalReporting.gov. Data that HHS does not currently collect are highlighted in yellow. Do not copy this highlighted information. Please enter the appropriate data for your organization in these required fields. For assistance with entering these data please contact FederalReporting.gov.

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Award Detail for: ANTICONVULSANT EFFECTS OF NOVEL CONCENTRIC RING ELECTRODE ELECTRICAL STIMULATION
UNIVERSITY OF RHODE ISLAND
DUNS Number: 796475382
70 LOWER COLLEGE ROAD
KINGSTON, RI 02881
Recipient Report: Grant or Loan
Prime Recipient

Reporting Information
Award Type Award Number Final Report
Grant 1R21NS061335-01A2 Recipient responsible for this data

Award Recipient Information
Recipient DUNS Number Recipient Account Number Recipient Congressional District
796475382 Recipient responsible for this data 2

Award Information
Funding Agency Code Awarding Agency Code Award Date
7529 7529 05-06-2009
Amount of Award Sub Account Number for Program Source (TAS)  
$ 181,276 Recipient responsible for this data
Program Source (TAS)* CFDA Number 
750901 93.701
Total Number of Sub Awards to Individuals Total Amount of Sub Awards to Individuals
Recipient responsible for this data Recipient responsible for this data
Total Number of Payments to Vendors less than $25,000/award Total Amount of Payments to Vendors less than $25,000/award
Recipient responsible for this data Recipient responsible for this data
Total Number of Sub Awards less than $25,000/award Total Amount of Sub Awards less than $25,000/award
Recipient responsible for this data Recipient responsible for this data
Award Description
DESCRIPTION (provided by applicant): Epilepsy, characterized by recurring seizures, is one of the most prevalent neurological disorders in the U.S. Despite decades of research, new anticonvulsant drugs, and advances in surgical therapy, a large number of patients suffer from intractable epilepsy or the side effects of drugs or surgical treatment. Brain stimulation for epilepsy has shown promise but requires further research. The long-term goal of the investigators is to develop effective non-invasive and minimally invasive electrical stimulation therapies for intractable epilepsy. Non-invasive transcutaneous electrical stimulation (TcES) via unique concentric ring electrodes on the scalp surface is proposed as an innovative approach to seizure control. Noninvasive methods for stimulation-induced seizure control avoid complications associated with intracerebral implants. The objective of this R21 project is to investigate in laboratory rats anticonvulsant and safety of TcES via concentric ring electrodes on the scalp surface. Based on promising preliminary results, three hypotheses are behind this research: " Hypothesis 1: TcES via concentric ring electrodes on the scalp surface has anticonvulsant effects. " Hypothesis 2: {The suppression of pilocarpine (PILO)-induced status epilepticus (SE) by TcES via concentric ring electrodes reduces SE-provoked neuronal death.} " Hypothesis 3: Effective TcES parameters do not cause damage to rat scalp or brain tissue. To achieve the project objective and test the hypothesis, three specific aims are set: " Aim 1: Analyze the effects of TcES via concentric ring electrodes on electrographic activity, behavioral manifestations, severity, latency to onset, and threshold of pentylenetetrazole (PTZ)-induced seizures in rats. (test Hypothesis 1) " Aim 2: {Verify the suppression of PILO-induced SE by TcES via concentric ring electrodes through histopathological evaluation of neuronal integrity.} (test Hypothesis 2) " Aim 3: Assess potential tissue damage due to TcES via concentric ring electrodes through histomorphological analysis. The integrity of both scalp and brain tissue will be assessed. (test Hypothesis 3) As an initial phase of our research, this R21 project lays the foundation for future investigations of TcES in additional areas of importance. PUBLIC HEALTH RELEVANCE: If the proposed research is successful, in the future TcES may promise a viable non-invasive therapy for intractable epilepsy. A non-invasive therapeutic strategy for bedside and/or out-of-hospital intervention can significantly improve morbidity and mortality, as well as reduce risk and cost of treatment.

Project Information
Project Name or
Project/Program Title
Project Status Total Federal Amount ARRA Funds
Received/Invoiced
ANTICONVULSANT EFFECTS OF NOVEL CONCENTRIC RING ELECTRODE ELECTRICAL STIMULATION Recipient responsible for this data Recipient responsible for this data
Number of Jobs Description of Jobs Created
Recipient responsible for this data Recipient responsible for this data
Quarterly Activities/Project Description
Recipient responsible for this data
 
Activity Code (NAICS or NTEE-NPC)
1Recipient responsible for this data2Recipient responsible for this data
3Recipient responsible for this data4Recipient responsible for this data
5Recipient responsible for this data6Recipient responsible for this data
7Recipient responsible for this data8Recipient responsible for this data
9Recipient responsible for this data10Recipient responsible for this data
Total Federal Amount of ARRA
Expenditure
Total Federal ARRA
Infrastructure Expenditure
Infrastructure Contact Name
Recipient responsible for this data Recipient responsible for this data Recipient responsible for this data
Infrastructure Contact Email Infrastructure Contact Phone Infrastructure Contact Phone Ext.
Recipient responsible for this data Recipient responsible for this data Recipient responsible for this data
Infrastructure Contact Street Address 1 Infrastructure Contact Street Address 2 Infrastructure Contact Street Address 3
70 LOWER COLLEGE ROAD Not Available Recipient responsible for this data
Infrastructure City Infrastructure State Infrastructure ZIP Code+4
KINGSTON RI 02881
Infrastructure Purpose and Rationale
Recipient responsible for this data

Primary Place of Performance
Street Address 1 Street Address 2 City
RESEARCH OFFICE70 LOWER COLLEGE ROAD, SUITE 2 Recipient responsible for this data KINGSTON
State Zip Code+4 Congressional District
RI 28810811 2
Country  
US

Recipient Highly Compensated Officers
Prime Recipient Indication of Reporting Applicability # Officer Name Officer Compensation
Recipient responsible for this data 1 Recipient responsible for this data Recipient responsible for this data
2 Recipient responsible for this data Recipient responsible for this data
3 Recipient responsible for this data Recipient responsible for this data
4 Recipient responsible for this data Recipient responsible for this data
5 Recipient responsible for this data Recipient responsible for this data

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USE IN THE RECIPIENT REPORT

The information provided by this tool is baseline data that the Recipient should include in the Recipient Report that must be submitted to FederalReporting.gov beginning October 1, 2009. The data from this tool can be cut and pasted directly into the Recipient Report.