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Research on the Epidemiology,Prevention,Vaccine Effectiveness and Treatment of Influenza and Other Respiratory Viruses in South Africa.09

Award Number: U01IP001048
ORGANIZATION: NATIONAL CENTER FOR IMMUNIZATION AND RESPIRATORY DISEASES(NCIRD)
OPDIV: CDC
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

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PROJECT SUMMARY This project aims to generate a body of data that will assist in formulating appropriate policies for the reduction of morbidity and mortality associated with influenza and other respiratory pathogens. Specifically we aim to describe the burden, clinical spectrum, pathogenesis, transmission and outcomes of influenza and other respiratory pathogens in different age and risk groups in South Africa. We will assess the effectiveness and/or efficacy and safety of influenza vaccines in preventing laboratory-confirmed influenza in different risk groups of importance in low- and middle-income settings (for example pregnant women) as well as exploring alternate vaccination strategies such as targeting community transmitters. In order to achieve these objectives, we will use a combination of approaches including enhanced surveillance for pneumonia and influenza-like illness, community transmission studies, case-control studies, cohort studies, healthcare utilization surveys, vaccination demonstration projects and modelling. We will establish partnerships with relevant stakeholders locally and regionally to support research and surveillance activities, development of influenza vaccine production capacity and the translation of data into policy. Additional activities include conducting intensive community transmission studies to understand the community burden and transmission of influenza and interaction of influenza with other respiratory pathogens. We will use costing data obtained from surveillance combined with modelling approaches to evaluate cost-effectiveness of different influenza vaccination approaches. We will strengthen capacity to identify and respond to novel influenza viruses at the animal-human interface and work to build laboratory and epidemiology capacity for influenza surveillance in the country and the region.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2024 ( Subtotal = -$2 )
2024	2020	NATIONAL HEALTH LABORATORY SERVICE	1 MODDERFONTEIN ROAD	JOHANNESBURG	province			ZAF	Centers for Disease Control and Prevention Investigations and Technical Assistance	04	5	11/24/2023	ADMINISTRATIVE SUPPLEMENT ( + OR - ) (DISCRETIONARY OR BLOCK AWARDS)	$0
2024	2020	NATIONAL HEALTH LABORATORY SERVICE	1 MODDERFONTEIN ROAD	JOHANNESBURG	province			ZAF	Centers for Disease Control and Prevention Investigations and Technical Assistance	03	5	11/6/2023	ADMINISTRATIVE SUPPLEMENT ( + OR - ) (DISCRETIONARY OR BLOCK AWARDS)	-$2
														Subtotal = -$2

Issue Date FY: 2023 ( Subtotal = -$1 )
2023	2020	NATIONAL HEALTH LABORATORY SERVICE	1 MODDERFONTEIN ROAD	JOHANNESBURG	province			ZAF	Centers for Disease Control and Prevention Investigations and Technical Assistance	02	5	9/28/2023	ADMINISTRATIVE SUPPLEMENT ( + OR - ) (DISCRETIONARY OR BLOCK AWARDS)	$0
2023	2019	NATIONAL HEALTH LABORATORY SERVICE	1 MODDERFONTEIN ROAD	JOHANNESBURG	province			ZAF	Centers for Disease Control and Prevention Investigations and Technical Assistance	02	5	9/28/2023	ADMINISTRATIVE SUPPLEMENT ( + OR - ) (DISCRETIONARY OR BLOCK AWARDS)	-$1
2023	2018	NATIONAL HEALTH LABORATORY SERVICE	1 MODDERFONTEIN ROAD	JOHANNESBURG	province			ZAF	Centers for Disease Control and Prevention Investigations and Technical Assistance	02	5	9/28/2023	ADMINISTRATIVE SUPPLEMENT ( + OR - ) (DISCRETIONARY OR BLOCK AWARDS)	$0
2023	2017	NATIONAL HEALTH LABORATORY SERVICE	1 MODDERFONTEIN ROAD	JOHANNESBURG	province			ZAF	Centers for Disease Control and Prevention Investigations and Technical Assistance	02	5	9/28/2023	ADMINISTRATIVE SUPPLEMENT ( + OR - ) (DISCRETIONARY OR BLOCK AWARDS)	$0
2023	2016	NATIONAL HEALTH LABORATORY SERVICE	1 MODDERFONTEIN ROAD	JOHANNESBURG	province			ZAF	Centers for Disease Control and Prevention Investigations and Technical Assistance	02	5	9/28/2023	ADMINISTRATIVE SUPPLEMENT ( + OR - ) (DISCRETIONARY OR BLOCK AWARDS)	$0
														Subtotal = -$1

Issue Date FY: 2021 ( Subtotal = $0 )
2021	2020	NATIONAL HEALTH LABORATORY SERVICE	1 MODDERFONTEIN ROAD	JOHANNESBURG	province			ZAF	Centers for Disease Control and Prevention Investigations and Technical Assistance	01	5	9/1/2021	ADMINISTRATIVE SUPPLEMENT ( + OR - ) (DISCRETIONARY OR BLOCK AWARDS)	$0
2021	2019	NATIONAL HEALTH LABORATORY SERVICE	1 MODDERFONTEIN ROAD	JOHANNESBURG	province			ZAF	Centers for Disease Control and Prevention Investigations and Technical Assistance	01	5	9/1/2021	ADMINISTRATIVE SUPPLEMENT ( + OR - ) (DISCRETIONARY OR BLOCK AWARDS)	$0
														Subtotal = $0

Issue Date FY: 2020 ( Subtotal = $9,426,671 )
2020	2020	NATIONAL HEALTH LABORATORY SERVICE	1 MODDERFONTEIN ROAD	JOHANNESBURG	GAUTENG	2192		ZAF	Centers for Disease Control and Prevention Investigations and Technical Assistance	02	4	6/11/2020	ADMINISTRATIVE SUPPLEMENT ( + OR - ) (DISCRETIONARY OR BLOCK AWARDS)	$4,656,240
2020	2020	NATIONAL HEALTH LABORATORY SERVICE	1 MODDERFONTEIN ROAD	JOHANNESBURG	province	postal_code		ZAF	Centers for Disease Control and Prevention Investigations and Technical Assistance	00	5	8/18/2020	NON-COMPETING CONTINUATION	$4,770,431
2020	2019	NATIONAL HEALTH LABORATORY SERVICE	1 MODDERFONTEIN ROAD	JOHANNESBURG	GAUTENG	2192		ZAF	Centers for Disease Control and Prevention Investigations and Technical Assistance	02	4	6/11/2020	ADMINISTRATIVE SUPPLEMENT ( + OR - ) (DISCRETIONARY OR BLOCK AWARDS)	$0
2020	2019	NATIONAL HEALTH LABORATORY SERVICE	1 MODDERFONTEIN ROAD	JOHANNESBURG	GAUTENG	2192		ZAF	Centers for Disease Control and Prevention Investigations and Technical Assistance	01	4	11/5/2019	ADMINISTRATIVE SUPPLEMENT ( + OR - ) (DISCRETIONARY OR BLOCK AWARDS)	$0
2020	2019	NATIONAL HEALTH LABORATORY SERVICE	1 MODDERFONTEIN ROAD	JOHANNESBURG	province	postal_code		ZAF	Centers for Disease Control and Prevention Investigations and Technical Assistance	00	5	8/18/2020	NON-COMPETING CONTINUATION	$0
														Subtotal = $9,426,671

Issue Date FY: 2019 ( Subtotal = $1,250,000 )
2019	2019	NATIONAL HEALTH LABORATORY SERVICES	1 MODDERFONTEIN ROAD	JOHANNESBURG	province	postal_code		ZAF	Centers for Disease Control and Prevention Investigations and Technical Assistance	00	4	6/24/2019	NON-COMPETING CONTINUATION	$1,250,000
														Subtotal = $1,250,000

Issue Date FY: 2018 ( Subtotal = $2,190,000 )
2018	2018	NATIONAL HEALTH LABORATORY SERVICES	1 MODDERFONTEIN ROAD	JOHANNESBURG		2192		ZAF	Centers for Disease Control and Prevention Investigations and Technical Assistance	00	3	8/2/2018	NON-COMPETING CONTINUATION	$2,190,000
2018	2017	NATIONAL HEALTH LABORATORY SERVICES	1 MODDERFONTEIN ROAD	JOHANNESBURG		2192		ZAF	Centers for Disease Control and Prevention Investigations and Technical Assistance	001	2	11/9/2017	NON-COMPETING CONTINUATION	$0
2018	2016	NATIONAL HEALTH LABORATORY SERVICES	1 MODDERFONTEIN ROAD	JOHANNESBURG		2192		ZAF	Centers for Disease Control and Prevention Investigations and Technical Assistance	000	1	10/18/2017	NEW	$0
														Subtotal = $2,190,000

Issue Date FY: 2017 ( Subtotal = $3,120,562 )
2017	2017	NATIONAL HEALTH LABORATORY SERVICES	1 MODDERFONTEIN ROAD	JOHANNESBURG		2192		ZAF	Centers for Disease Control and Prevention Investigations and Technical Assistance	001	2	8/2/2017	NON-COMPETING CONTINUATION	$3,120,562
2017	2016	NATIONAL HEALTH LABORATORY SERVICES	1 MODDERFONTEIN ROAD	JOHANNESBURG		2192		ZAF	Centers for Disease Control and Prevention Investigations and Technical Assistance	000	1	5/4/2017	NEW	$0
														Subtotal = $3,120,562

Issue Date FY: 2016 ( Subtotal = $3,908,000 )
2016	2016	NATIONAL INSTITUTE FOR COMMUNICABLE DISEASES	POST OFFICE BOX 1038	JOHANNESBURG				ZAF	Centers for Disease Control and Prevention Investigations and Technical Assistance	000	1	8/26/2016	NEW	$3,908,000
														Subtotal = $3,908,000

Grand Total All Awards = $19,895,230

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Research on the Epidemiology,Prevention,Vaccine Effectiveness and Treatment of Influenza and Other Respiratory Viruses in South Africa.09

Award Number: U01IP001048

ORGANIZATION: NATIONAL CENTER FOR IMMUNIZATION AND RESPIRATORY DISEASES(NCIRD)

OPDIV: CDC

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

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